原发性主动脉附壁血栓的研究进展

Research progress of primary aortic mural thrombus

原发性主动脉附壁血栓是一种比较少见的临床疾病,其发病机制尚未明确,除高凝状态为目前公认的危险因素外,其他相关因素也在文献中被提及。主动脉峡部是血栓的好发部位,其原因可能与该处的解剖特点与血流动力学有关。该疾病发病隐匿,并发症凶险,最佳治疗策略目前仍未明确,单纯抗凝治疗、主动脉开放手术与腔内治疗均有成功报道。本文针对原发性主动脉附壁血栓的研究进展进行综述报道。

Primary aortic mural thrombus(PAMT)is a relatively rare clinical disease with unclear pathogenesis.In addition to hypercoagulability as a recognized risk factor,other related factors have been mentioned in the literatures.Aortic isthmus is the most common site of thrombosis,which may be related to its anatomical characteristics and hemodynamics.The onset of this disease is insidious,but the complications are dangerous.At present,the best treatment strategy for this disease is not clear,and simple anticoagulant therapy,aortic open surgery and endovascular treatment have been reported successfully.This article reviews the research progress of primary aortic mural thrombosis and reports as follows.