饮食模式与代谢相关脂肪性肝病关系的研究进展

Research progress on the relationship between dietary patterns and metabolic-associated fatty liver disease

代谢相关脂肪性肝病已成为一种全球主要的健康负担,由于其复杂的发病机制,迄今仍未有特效治疗药物。饮食结构与代谢相关脂肪性肝病的发生与发展密切相关,通过均衡饮食实现减重是治疗代谢相关脂肪性肝病的基石。现将代谢相关脂肪性肝病与地中海饮食、得舒饮食、限能量平衡膳食、低脂、低碳水化合物饮食、西方饮食、动物性食物饮食、传统饮食及其他饮食模式关系的国内外研究进展加以总结讨论,梳理各饮食结构对代谢相关脂肪性肝病的防治或诱发作用,以及各饮食结构存在的、有待加以深入研究的若干问题,以期为后续研究提供参考。

Globally,metabolic-asssociated fatty liver disease has become a significant health burden due to its complex pathogenesis,and there are no specific and effective therapeutic drugs to date.The onset and progression of metabolic-asssociated fatty liver disease is closely associated with improper dietary habits.The cornerstone to treat metabolic-asssociated fatty liver disease is weight loss through a well-balanced diet.This article summarizes and discusses the research progress at home and abroad in relationship to metabolic-asssociated fatty liver disease and dietary patterns such as the Mediterranean diet,the DASH diet,an energy-restricted balanced diet,a low fat diet,a low carbohydrate diet,a western diet,an animal food diet,a traditional diet,and others.In addition,it categorizes the effects of various dietary patterns on the prevention,treatment,or induction of several issues that need further metabolic-asssociated fatty liver disease research for subsequent reference.