痰热清注射液联合头孢哌酮钠舒巴坦钠治疗非重症社区获得性肺炎的效果分析

Efficacy Analysis of Tanreqing Injection Combined with Cefoperazone Sodium and Sulbactam Sodium in Treatment of Non-Severe Community-Acquired Pneumonia

目的:观察痰热清注射液联合头孢哌酮钠舒巴坦钠治疗非重症社区获得性肺炎的效果。方法:选取2020年1月-2021年10月临沂市中心医院呼吸内科收治的70例非重症社区获得性肺炎患者作为研究对象,按照随机数表法分为两组,各35例。对照组予以头孢哌酮钠舒巴坦钠治疗,观察组在对照组基础上加用痰热清注射液治疗。比较两组治疗效果、症状改善时间、血清C反应蛋白(CRP)、降钙素原(PCT)水平及不良反应发生情况。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。观察组发热消退时间、咳嗽缓解时间、肺啰音改善时间均短于对照组,差异有统计学意义(P<0.05)。治疗前,两组CRP、PCT水平比较,差异无统计学意义(P>0.05);治疗后,两组CRP、PCT水平均低于治疗前,且观察组均低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在治疗非重症社区获得性肺炎过程中,应用痰热清注射液联合头孢哌酮钠舒巴坦钠的效果良好,可降低患者血清CRP、PCT水平,安全性高,值得应用并予以推广。

Objective:To observe the effect of Tanreqing Injection combined with cefoperazone sodium and sulbactam sodium in treatment of non-severe community-acquired pneumonia.Methods:Seventy patients with non-severe community-acquired pneumonia who were admitted to Department of Respiratory Medicine at Linyi Central Hospital from January 2020 to October 2021 were selected as the study subjects,and they were divided into two groups according to random number table method,with 35 cases in each group.The control group was treated with cefoperazone sodium and sulbactam sodium,and the observation group was additionally treated with Tanreqing Injection on the basis of control group.The treatment effect,symptom improvement time,serum C reactive protein(CRP),procalcitonin(PCT)and adverse reactions in the two groups were compared.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The fever resolution time,cough relief time and pulmonary rale improvement time in the observation group were all shorter than those in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in the CRP and PCT levels between the two groups(P<0.05);After treatment,the CRP and PCT levels of the two groups were lower than those before treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:In the treatment of non-severe community-acquired pneumonia,the combination of Tanreqing Injection with cefoperazone sodium and sulbactam sodium is effective,it can reduce serum CRP and PCT levels of patients,with high safety,and it is worthy of application and promotion.