摘要
The study of toxicological mechanism is an important aspect in the field of environmental and occupational health related disease control.With the progress of science and technology,the research of toxicological mechanism has made great progress.In recent years,the application of"omics"in the study of toxicological mechanisms has attracted widespread attention from scholars in the field."Omics,"such as Genomics and Proteomics[1].More and more studies have found that many important life activities and diseases are not only related to protein abundance,but more importantly are regulated by various post-translational modifications(PTMs)of proteins.In-depth study of protein post-translational modification is of great significance for revealing the mechanism of life activities,screening clinical markers of diseases,and identifying drug targets.