摘要
脐带间充质干细胞(UC-MSCs)是一种免疫原性低、易于获取和扩增的成体干细胞。UC-MSCs可以调节伤口炎性反应水平,促进血管形成、细胞增殖,抑制瘢痕形成,诱导皮肤附件形成。UC-MSCs联合其他药物作用于伤口可以促进UC-MSCs的黏附、存活、迁移和增殖等。
Umbilical cord mesenchymal stem cells(UC-MSCs)are a kind of adult stem cells with low immunogenicity,which are easy to collect and to expand in vitro.UC-MSCs can regulate wound inflammation,promote angiogenesis and cell proliferation,inhibit scar formation and induce the formation of skin appendages.UC-MSCs combined with other drugs can promote the adhesion,survival,migration and proliferation of UC-MSCs.
作者
吴文哲
孙建伟
付长秀
黄李晨露
郑永钦
贺军栋
WU Wen-zhe;SUN Jian-wei;FU Chang-xiu;HUANG Li-chen-lu;ZHENG Yong-qin;HE Jun-dong(Medical Faculty,Kunming University of Science and Technology,Kunming 650000;Department of Endocrinology and Metabolism,the First People's Hospital of Yunnan Province,the Affiliated Hospital of Kunming University of Science and Technology,Kunming 650000,China;Department of Breast and Thyroid Surgery,the First People's Hospital of Yunnan Province,the Affiliated Hospital of Kunming University of Science and Technology,Kunming 650000,China)
出处
《基础医学与临床》
2022年第11期1771-1775,共5页
Basic and Clinical Medicine
基金
云南省中青年学术和技术带头人后备人才(2018HB050)
云南省“万人计划”青年拔尖人才专项(YNWR-QNBJ-2018-070)。
关键词
脐带间充质干细胞
炎性反应
增殖
黏附
迁移
umbilical cord mesenchymal stem cells
inflammation response
proliferation
adhesion
migration
