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脐带间充质干细胞修复皮肤创伤的研究进展

Research progress of umbilical cord mesenchymal stem cells in repairing skin wounds
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摘要 脐带间充质干细胞(UC-MSCs)是一种免疫原性低、易于获取和扩增的成体干细胞。UC-MSCs可以调节伤口炎性反应水平,促进血管形成、细胞增殖,抑制瘢痕形成,诱导皮肤附件形成。UC-MSCs联合其他药物作用于伤口可以促进UC-MSCs的黏附、存活、迁移和增殖等。 Umbilical cord mesenchymal stem cells(UC-MSCs)are a kind of adult stem cells with low immunogenicity,which are easy to collect and to expand in vitro.UC-MSCs can regulate wound inflammation,promote angiogenesis and cell proliferation,inhibit scar formation and induce the formation of skin appendages.UC-MSCs combined with other drugs can promote the adhesion,survival,migration and proliferation of UC-MSCs.
作者 吴文哲 孙建伟 付长秀 黄李晨露 郑永钦 贺军栋 WU Wen-zhe;SUN Jian-wei;FU Chang-xiu;HUANG Li-chen-lu;ZHENG Yong-qin;HE Jun-dong(Medical Faculty,Kunming University of Science and Technology,Kunming 650000;Department of Endocrinology and Metabolism,the First People's Hospital of Yunnan Province,the Affiliated Hospital of Kunming University of Science and Technology,Kunming 650000,China;Department of Breast and Thyroid Surgery,the First People's Hospital of Yunnan Province,the Affiliated Hospital of Kunming University of Science and Technology,Kunming 650000,China)
出处 《基础医学与临床》 2022年第11期1771-1775,共5页 Basic and Clinical Medicine
基金 云南省中青年学术和技术带头人后备人才(2018HB050) 云南省“万人计划”青年拔尖人才专项(YNWR-QNBJ-2018-070)。
关键词 脐带间充质干细胞 炎性反应 增殖 黏附 迁移 umbilical cord mesenchymal stem cells inflammation response proliferation adhesion migration
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