急性重症左心衰患者行呼吸机治疗的效果及对血气指标的影响分析

Analysis of the effect of ventilator therapy in patients with acute severe left heart failure and its influence on blood gas indexes

目的分析急性重症左心衰患者行呼吸机治疗的效果及对血气指标的影响。方法118例急性重症左心衰患者,按照随机抽签法分为观察组与对照组,各59例。对照组给予常规治疗,观察组在常规治疗基础上给予呼吸机治疗。比较两组疗效、心衰因子[脑钠肽(BNP)、心钠肽(ANP)]水平、治疗前后的血气指标[动脉血氧分压(PaO_(2))、二氧化碳分压(PaCO_(2))、pH值]水平。结果观察组治疗总有效率为96.61%,高于对照组的84.75%,差异有统计学意义(P<0.05)。观察组BNP(271.02±32.13)pg/ml、ANP(170.18±30.05)pg/ml均低于对照组的(353.92±36.27)、(182.31±30.10)pg/ml,差异有统计学意义(P<0.05)。治疗后,观察组PaO_(2)(83.44±6.57)mm Hg(1 mm Hg=0.133 kPa)、pH值(7.36±0.07)高于对照组的(72.63±6.23)mm Hg、(7.34±0.03),PaCO_(2)(42.35±3.57)mm Hg低于对照组的(50.63±4.23)mm Hg,差异有统计学意义(P<0.05)。结论采用呼吸机治疗急性重症左心衰患者效果显著,可改善血气指标与心衰因子水平。

Objective To analyze the effect of ventilator therapy in patients with acute severe left heart failure and its influence on blood gas indexes.Methods A total of 118 patients with acute severe left heart failure were randomly divided into observation group and control group,with 59 cases in each group.The control group received conventional treatment,and the observation group received ventilator therapy on the basis of conventional treatment.Both groups were compared in terms of clinical efficacy,heart failure factor[brain natriuretic peptide(BNP),atrial natriuretic peptide(ANP)]levels,blood gas indexes[arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2)),and pH value before and after treatment.Results The total effective rate of the observation group was 96.61%,which was higher than 84.75%of the control group,and the difference was statistically significant(P<0.05).The BNP(271.02±32.13)pg/ml and ANP(170.18±30.05)pg/ml in the observation group were lower than(353.92±36.27)and(182.31±30.10)pg/ml in the control group,and the differences were statistically significant(P<0.05).After treatment,the PaO_(2)(83.44±6.57)mm Hg(1 mm Hg=0.133 kPa)and pH value(7.36±0.07)in the observation group were higher than(72.63±6.23)mm Hg,(7.34±0.03)in the control group;the PaCO_(2)(42.35±3.57)mm Hg in the observation group was lower than(50.63±4.23)mm Hg in the control group;the differences were all statistically significant(P<0.05).Conclusion Ventilator therapy is effective for patients with acute severe left heart failure,and can improve the blood gas indicators and heart failure factor levels.