腹腔镜胃癌根治术治疗进展期胃癌的效果分析

Analysis of the effect of laparoscopic radical gastrectomy for advanced gastric cancer

目的探究腹腔镜胃癌根治术治疗进展期胃癌的临床效果。方法100例进展期胃癌患者,随机分为对照组和观察组,每组50例。对照组患者应用开腹手术治疗,观察组患者应用腹腔镜胃癌根治术治疗。比较两组患者手术相关指标(淋巴结清扫数目、肿瘤直径、手术时间、术中出血量、切口大小)、术后恢复情况(术后排气时间、胃肠减压停止时间、术后下床活动时间、住院时间)、手术并发症发生情况。结果观察组患者淋巴结清扫数目(22.69±3.58)个、肿瘤直径(4.25±1.02)cm与对照组的(22.79±3.14)个、(4.02±1.34)cm比较,差异均无统计学意义(P>0.05);观察组手术时间(143.20±12.54)min短于对照组的(180.45±20.19)min,术中出血量(134.96±20.42)ml少于对照组的(352.14±30.46)ml,切口大小(5.69±1.43)cm小于对照组的(20.48±4.25)cm,差异均具有统计学意义(P<0.05)。观察组患者术后排气时间(4.05±0.65)d、胃肠减压停止时间(4.12±0.87)d、术后下床活动时间(2.68±0.38)d、住院时间(12.68±2.33)d均短于对照组的(5.38±0.63)、(5.32±0.74)、(4.52±0.84)、(17.76±3.41)d,差异均具有统计学意义(P<0.05)。观察组手术并发症发生率8.00%低于对照组的24.00%,差异具有统计学意义(P<0.05)。结论给予进展期胃癌患者腹腔镜手术治疗,术中切口小、出血量少,有助于缩短术后恢复时间,并减少感染、出血等各项并发症的发生,利于预后。

Objective To investigate the clinical effect of laparoscopic radical gastrectomy for advanced gastric cancer.Methods A total of 100 patients with advanced gastric cancer were randomly divided into control group and observation group,with 50 cases in each group.Patients in the control group were treated with open surgery,and patients in the observation group were treated with laparoscopic radical gastrectomy.Both groups were compared in terms of surgery-related indicators(number of lymph nodes dissection,tumor diameter,operation time,intraoperative blood loss,incision size),postoperative recovery(postoperative exhaust time,duration of gastrointestinal decompression,postoperative ambulation time,hospitalization time),and surgical complications.Results The number of lymph nodes dissection in the observation group was(22.69±3.58)nodes,the tumor diameter was(4.25±1.02)cm,and the differences were not statistically significant compared with(22.79±3.14)nodes and(4.02±1.34)cm in the control group(P>0.05).The operation time(143.20±12.54)min of the observation group was shorter than(180.45±20.19)min of the control group;the intraoperative blood loss(134.96±20.42)ml of the observation group was less than(352.14±30.46)ml of the control group;the incision size(5.69±1.43)cm of the observation group was smaller than(20.48±4.25)cm of the control group;the differences were all statistically significant(P<0.05).In the observation group,the postoperative exhaust time was(4.05±0.65)d,the duration of gastrointestinal decompression was(4.12±0.87)d,the postoperative ambulation time was(2.68±0.38)d,and the hospitalization time was(12.68±2.33)d,which were shorter than(5.38±0.63),(5.32±0.74),(4.52±0.84),and(17.76±3.41)d in the control group,and the differences were all statistically significant(P<0.05).The incidence of surgical complications 8.00%in the observation group was lower than 24.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery for patients with advanced gastric cancer has the advantages of small incision and less blood loss,and is helpful to shorten the postoperative recovery time,reduce the incidence of infection,bleeding,which is beneficial to the prognosis.