三维辐射变色丁二炔囊泡凝胶剂量计研究

Study on 3D Radiochromic Diacetylene Vesicle Gel Dosimeters

将10,12-二十五碳二炔酸自组装成纳米剂量囊泡后,均匀分散于组织等效的凝胶载体中研制出用于三维剂量分布测量的辐射变色凝胶剂量计。用电镜观测了囊泡形貌;用Co-60源对凝胶剂量计进行辐照;测试并研究了凝胶剂量计对剂量的变色响应、辐射后效应、扩散效应等剂量学性能;利用该凝胶剂量计实测了Co-60射线在组织等效凝胶中的深度剂量分布。结果表明:该辐射变色凝胶剂量计在100~1000 Gy剂量范围内对γ射线辐照具有良好的剂量响应线性,同时克服了扩散效应、辐射后效应、成型能力差等现有凝胶剂量计的不足。该辐射变色凝胶剂量计可用于辐射加工、科学实验和放射治疗等三维剂量分布测量。

Through dispersing nano vesicles self-assembled by 10,12-Pentacosadiynoic acid into the tissue equivalent gel carrier, a novel radiochromic gel dosimeter was developed for the 3D dose distribution measurement. The vesicle morphology was observed by electron microscopy and the irradiation of gel dosimeter was carried out with a CO-60 source. The gel dosimeter’s dosimetry performance such as discoloration response to dose, post radiation effect, diffusion effect and et al were test and studied. The depth-dose distribution of CO-60 ray was measured by the radiochromic gel dosimeter. Results indicate that the radiochromic gel dosimeter has good linear dose response to the γ-ray irradiation in the dose range of 100-1000 Gy, and overcomes the shortage of the existing gel dosimeter such as the diffusion effect, post radiation effect and poor forming ability. The radiochromic gel dosimeter can be used to measure three-dimensional dose distribution in radiation processing, scientific experiments and radiotherapy.