白血病与淋巴瘤的微小残留病检测手段前景及临床意义探讨

Prospects and clinical significance of detection methods for minimal residual disease in the field of leukemia and lymphoma

不同的方法与技术的微小残留病检测限具有差异。近年来随着分子检测技术快速发展,一系列新兴的技术也在微小残留病(MRD)监测中逐渐得到认可与广泛应用。基于精确度的方法将使我们能够根据治疗周期后的MRD正确的对每个患者进行分层。本文汇总了近年来用于微小残留病监测的新技术,并就各自在血液肿瘤领域的应用现状及特点进行综述。

Different methods and techniques have different detection limits for minimal residual disease.In recent years,with the rapid development of molecular detection technology,a series of emerging technologies have gradually been recognized and widely used in the monitoring of minimal residual diseases(MRD).Precision-based approaches will allow us to correctly stratify each patient based on the MRD after a treatment cycle.This paper summarizes recent new technologies for the monitoring of minimal residual disease,and reviews their current status and characteristics in the field of hematology.