摘要
B群脑膜炎球菌疫苗的研发包括外膜囊泡(OMV)疫苗和重组蛋白疫苗两条技术路线, 本文拟就B群脑膜炎球菌OMV疫苗的研发、生产和应用进展进行综述, 以期为我国B群脑膜炎球菌OMV疫苗的研发提供参考。
This research and development of MenB meningococcal vaccines includes two technical routes:outer membrane vesicle(OMV)vaccines and recombinant protein vaccines.This article intends to review the development,production and application of MenB meningococcal OMV vaccines in order to provide a reference for the development of MenB meningococcal OMV vaccine in China.
作者
岳萌萌
徐娟
徐丽
邵祝军
Yue Mengmeng;Xu Juan;Xu Li;Shao Zhujun(National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;School of Public Health,Nanjing Medical University,Nanjing 211166,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2022年第9期1333-1340,共8页
Chinese Journal of Preventive Medicine
基金
北京市自然科学基金(L212011)。
关键词
脑膜炎球菌
疫苗
B群
外膜囊泡
Neisseria meningitidis
Vaccine
Serogroup B
Outer membrane vesicles
