血清hs-cTnⅠ与老年冠心病患者PCI术后心血管不良事件的相关性

Correlation between serum hs-cTnⅠ and cardiovascular adverse events in elderly patients with coronary heart disease after PCI

目的:研究血清超敏肌钙蛋白Ⅰ(hs-cTnⅠ)水平与老年冠心病患者经皮冠状动脉介入术(PCI)术后心血管不良事件(MACE)的相关性。方法:纳入2018年8月~2020年3月期间在我院的老年冠心病患者80例为研究对象。统计各项临床资料,包括年龄、性别、疾病诊断、药物使用及实验室检查指标等。所有患者出院后均接受12个月的随访,观察患者MACE发生情况。分析血清hs-cTnⅠ水平对老年冠心病患者PCI术后发生MACE的预测价值。结果:80例老年冠心病患者中,发生MACE 15例,占18.75%。MACE组年龄、hs-cTnⅠ水平及吸烟患者占比显著高于非MACE组。hs-cTnⅠ预测老年冠心病患者PCI术后MACE发生的曲线下面积为0.769,敏感度为72.45%,特异度为70.11%。年龄、吸烟及hs-cTnⅠ是老年冠心病患者PCI术后MACE发生的独立影响因素。结论:血清hs-cTnⅠ水平与老年冠心病患者PCI术后MACE发生密切相关。

Objective To study the correlation between serum high-sensitivity troponin Ⅰ (hs-cTnⅠ) and cardiovascular adverse events after percutaneous coronary intervention (PCI) in elderly patients with coronary heart disease.Methods A total of 80 elderly patients with coronary heart disease in our hospital from August 2018 to March 2020 were included as the research objects.The clinical data,including age,sex,disease diagnosis,drug use and laboratory indicators,were collected.All patients were followed up for 12 months after discharge to observe the occurrence of MACE.To analyze the predictive value of serum hs-cTnⅠ level for the occurrence of MACE in elderly patients with coronary heart disease after PCI.Results Among the 80 elderly patients with coronary heart disease,MACE occurred in 15 cases,accounting for 18.75%.The age,hs-cTnⅠ level and the proportion of smoking patients in the MACE group were significantly higher than those in the non-MACE group,and the differences were statistically significant.The area under the curve of hs-cTnⅠ in predicting the occurrence of MACE in elderly patients with coronary heart disease after PCI was 0.769,the sensitivity was 72.45%,and the specificity was 70.11%.Age,smoking and hs-cTnⅠ were independent influencing factors of mace after PCI in elderly patients with coronary heart disease.Conclusion Serum hs-cTnⅠ level is closely related to the occurrence of MACE in elderly patients with coronary heart disease after PCI.