微针的制备及应用研究

Study on Preparation and Application of Microneedles

本文主要针对微针的材质、类别、设计、制备与加工方法进行分析,列举了金属、硅、聚合物和一些其他的微针材料。同时也对微针的应用,例如经皮给药的方法、途径以及影响进行了说明。此外,对其作用于糖尿病、皮肤病和其他疾病及其复合应用进行了简单分析。聚合物微针和新型微针的发展可以显著提高药物的透皮速率,但是在安全性上还有待进一步研究。

This paper mainly focuses on the material, classification, design, preparation and processing methods of the microneedles, including metal, silicon, polymer and some other microneedle materials. At the same time, the applications of microneedles, such as the method, route, and influence of transdermal drug delivery are also explained. In addition, a brief analysis of its effects on diabetes, dermatology, and other diseases and their combined applications is performed. The development of polymer microneedles and novel microneedles can significantly improve the transdermal rate of drugs, but their safety needs further study.