变态反应检测与诊断的临床应用及意义

Clinical use and significance of allergy testing and diagnostics

变态反应疾病是当今全球最常见的疾病之一,而且疾病负担继续在增加。明确变应原致敏并识别引起变态反应疾病的变应原对于制定疾病管理策略至关重要。介绍目前国内外在诊断IgE介导的Ⅰ型变态反应中最常用的体内和体外检测方法及其临床意义。

Allergic diseases are among the most prevalent diseases worldwide and their burden on healthcare systems continues to increase. Confirmation of allergen sensitization and the identification of causal allergens are essential for developing management strategies for these maladies. This paper provides an updated introduction of the most commonly used detection methods, both in vivo and in vitro, in the diagnosis of type I IgE-mediated allergy and its clinical significance.