摘要
探讨习练太极拳对久坐少动老年人机体血浆8-OHdG和OGG1的影响,方法为对10名健康老年人进行为期16周(5次/周、70分钟/次)的简化太极拳练习干预。干预前(0周)、第8周、第12周及第16周于肘静脉采血3ml,并应用分光光度计和酶联免疫法测试血浆8-OHdG、OGG1及SOD等氧化应激指标。与干预前相比较,血浆8-OHdG在第8和第12周明显上升(P<0.05),血浆OGG1的活性在第8周开始明显提高(P<0.05),血浆SOD和羟自由基抑制能力(OH·-IC)在第8、12和16周均有显著提高(P<0.05),GPX和GSH干预前后无明显变化(P>0.05);MDA从第8周起明显下降(P<0.05)。结论表明:16周太极拳练习可有效改善久坐老人DNA碱基的损伤及其修复能力,且从第8周开始便可获得这种效应。
Objective:To investigate the effects of 16-week Tai Chi exercise on plasma 8-OHdG and OGG1 in sedentary elderly.Methods:10 healthy elderly were intervened by the simplified Tai Chi programfor 16 weeks(5 times/week,70 minutes/time).3 ml of blood was collected from the elbow vein at 0 weeks(before intervention),8^(th) week,12^(th) week and 16^(th) week.Plasma 8-OHdG,OGG1,and oxidative stress indicators such as SOD were measured by the methods of spectrophotometer and enzyme-linked immunoassay.Results:plasma 8-OHdG increased significantly at 8-and 12-week(P<0.05)compared with baseline.The activity of OGG1 increased significantly from 8-week(P<0.05).Plasma SOD and hydroxyl radical inhibition(OH·-IC)were significantly increased at 8-,12-,and 16-week(P<0.05);GPx and GSH did not change significantly(P>0.05);MDA decreased significantly from 8-week(P<0.05).Conclusion:16-week Tai Chi exercise is effectively to improve the ability of DNA base damage and its repair in the sedentary healthy elderly,and this effect can be obtained from the 8^(th) week.
作者
黄兴裕
吴秀华
HUANG Xing-yu;WU Xiu-hua(Physical Education College of Gannan Normal University,Ganzhou 341000,China;Science and Technology College of Gannan Normal University,Ganzhou 341000,China)
出处
《体育科学研究》
2022年第5期67-73,共7页
Sports Science Research
基金
江西省教育科学规划项目(17YB167)。
