抗疫强身功对新型冠状病毒奥密克戎变异株感染轻症和无症状患者核酸转阴率和焦虑情绪影响的临床研究

Influence of Kangyi Qiangshen Gong intervention on nucleic acid negative conversion rate and anxiety in patients with mild and asymptomatic infection of COVID⁃19 Omicron variant

目的观察规律习练抗疫强身功对新型冠状病毒奥密克戎变异株感染轻症和无症状患者7 d内核酸转阴率及焦虑情绪的影响。方法将580例新型冠状病毒奥密克戎变异株感染轻症和无症状患者随机分为治疗组和对照组,每组290例。对照组予荆银颗粒作为基础治疗药物并配合每日病毒核酸检测,治疗组在对照组干预措施基础上规律习练抗疫强身功。两组干预时间均为7 d,观察比较核酸转阴情况、住院时间及焦虑自评量表(SAS)相关评分。结果①试验期间,两组均未出现脱落病例,全部病例完成试验。②两组7 d内核酸转阴率比较,差异有统计学意义,治疗组明显高于对照组(P<0.05)。③两组平均住院时间比较,差异无统计学意义(P>0.05)。④干预治疗后,组间焦虑阳性率比较,差异有统计学意义(P<0.05)。⑤两组干预治疗前后组内SAS评分比较,差异均有统计学意义(P<0.05);组间干预治疗后比较,治疗组SAS评分明显低于对照组(P<0.05)。结论规律习练抗疫强身功有助于提高新型冠状病毒奥密克戎变异株感染轻症和无症状患者的7 d内核酸转阴率,缓解其焦虑情绪。

Objective To observe the effect of regular practice of Kangyi Qiangshen Gong(anti-epidemic and body-strengthening exercise)on the 7-day nucleic acid negative conversion rate and anxiety in patients with mild and asymptomatic infection of the COVID-19 Omicron variant.Methods A total of 580 patients with mild and asymptomatic infection of COVID-19 Omicron variant were randomly divided into a treatment group(n=290)and a control group(n=290).The control group was administered with Jingyin Granules as the basic treatment and daily nucleic acid test,while the treatment group was guided to practice Kangyi Qiangshen Gong regularly besides all the intervention measures in the control group.The interventions in both groups lasted 7 days.Nucleic acid negative conversion rate,hospitalization duration and self-rating anxiety scale(SAS)scores were observed and compared.Results①During the trial,there were no drop-outs in both groups,and all cases completed the trial.②There was statistically significant difference in the 7-day nucleic acid negative conversion rate between the two groups,and the treatment group had significantly higher rate than the control group(P<0.05).③There was no significant difference in the average length of stay in hospitals between the two groups(P>0.05).④After intervention,there was significant difference in the positive rate of anxiety between the two groups(P<0.05).⑤There were significant differences in SAS scores between the two groups before and after intervention(P<0.05);The SAS score of the treatment group was significantly lower than that of the control group after intervention(P<0.05).Conclusion Regular practice of Kangyi Qiangshen Gong can increase the nucleic acid negative conversion rate within 7 days in mildly infected and asymptomatic patients with the COVID-19 Omicron variant infection and relieve their anxiety.