摘要
诊断试验准确性比较(CDTA)研究是诊断准确性试验的一种,旨在同一诊断试验研究中比较2个及以上诊断试验的准确性。CDTA系统评价的GRADE证据确信度分级与单个诊断试验准确性系统评价不同,主要体现在研究设计的选择、偏倚风险的评估及试验准确性比较指标的使用等方面。本文重点介绍GRADE分级方法应用于CDTA系统评价的基本原理和方法,以促进国内学者对该方法的理解与应用。
Comparative diagnostic test accuracy study, a type of diagnostic accuracy test, aims to compare accuracy of two or more index tests in a study. The application of GRADE in comparative test accuracy differs from single test accuracy, mainly including the selection of appropriate comparative study designs, additional criteria for judging risk of bias, and the consequences of using comparative measures of test accuracy. The study focuses on basic principles and methods of GRADE approach in systematic reviews of comparative test accuracy to promote the understanding and application of the method by domestic scholars.
作者
陆瑶
杨秋玉
赖鸿皓
田晨
陈耀龙
田金徽
李霓
李江
葛龙
LU Yao;YANG Qiuyu;LAI Honghao;TIAN Chen;CHEN Yaolong;TIAN Jinhui;LI Ni;LI Jiang;GE Long(Evidence-Based Social Science Research Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Department of Social Science and Health Management,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Evidence Based Nursing Centre,School of Nursing,Lanzhou University,Lanzhou 730000,P.R.China;Evidence-based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province,Lanzhou 730000,P.R.China;National Cancer Center/National Cancer Clinical Medical Research Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,P.R.China)
出处
《中国循证医学杂志》
CSCD
北大核心
2022年第10期1233-1240,共8页
Chinese Journal of Evidence-based Medicine
基金
北京市科技新星计划项目(编号:Z201100006820070)
甘肃省科技计划项目(编号:20CX4ZA027、20CX9ZA112)。
