老年性胃溃疡相关因素临床研究

Clinical Study on Related Factors of Senile Gastric Ulcer

目的探讨老年性胃溃疡患病的相关因素。方法抽选丰城市中医院2019年1月-2020年1月收治的老年性胃溃疡患者52例设为观察组,同期选取的健康者52例设为对照组,采用单因素与多因素Logistic回归分析老年性胃溃疡患病的影响因素,并采用Spearman相关性分析各危险因素与老年性胃溃疡患者的关系。结果两组吸烟、饮酒、非甾体抗炎药服用史、不吃早餐、暴饮暴食、生活作息紊乱、幽门螺旋杆菌感染比较,差异有统计学意义(P<0.05);两组年龄、性别、是否为农民、是否有高中文化及以上比较,差异无统计学意义(P>0.05);多因素Logistic回归分析显示,饮酒、非甾体抗炎药服用史、生活作息紊乱、幽门螺旋杆菌感染是老年性胃溃疡患病的独立影响因素(P<0.05);Spearman秩相关性分析显示,饮酒、非甾体抗炎药服用史、生活作息紊乱、幽门螺旋杆菌感染与老年性胃溃疡患病呈正相关(P<0.05)。结论饮酒、非甾体抗炎药服用史、生活作息紊乱、幽门螺旋杆菌感染与老年性胃溃疡患病密切相关,是老年性胃溃疡患病的独立危险因素。

Objective To investigate the related factors of senile gastric ulcer.Methods A total of 52 patients with senile gastric ulcer admitted to Fengcheng Traditional Chinese Medicine Hospital from January 2019 to January 2020 were selected as the observation group,and 52 healthy people selected during the same period were selected as the control group.Univariate and multivariate Logistic regression analysis was used to analyze the influencing factors of senile gastric ulcer,and Spearman correlation was used to analyze the relationship between risk factors and senile gastric ulcer patients.Results There were significant differences in smoking,drinking,history of taking non-steroidal anti-inflammatory drugs,no breakfast,overeating,lifestyle disorders,and Helicobacter pylori infection between the two groups(P<0.05);there was no significant difference in age,gender,whether they were farmers,whether they had high school culture or above between the two groups(P>0.05).Multivariate Logistic regression analysis showed that drinking,history of non-steroidal anti-inflammatory drugs,lifestyle disorders,Helicobacter pylori infection were the independent factors of senile gastric ulcer(P<0.05).Spearman rank correlation analysis showed that drinking,history of non-steroidal anti-inflammatory drugs,lifestyle disorders,Helicobacter pylori infection were positively correlated with elderly gastric ulcer(P<0.05).Conclusion Alcohol consumption,non-steroidal anti-inflammatory drug use history,lifestyle disorders,Helicobacter pylori infection are closely related to the prevalence of senile gastric ulcer,and are independent risk factors for senile gastric ulcer.