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联合检测CK 19、MC、TPO及CD 56在甲状腺乳头状癌病理诊断中的意义

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摘要 目的:探讨联合检测细胞角蛋白19(CK19)、间皮细胞(MC)、甲状腺过氧化物酶(TPO)及神经细胞黏附分子(NCAM-1,又称CD56)在甲状腺乳头状癌病理诊断中的意义。方法:选择2020年1月至2021年11月武警四川省总队医院收治的102例甲状腺乳头状癌患者和98例甲状腺良性病变患者作为研究对象。将其中98例甲状腺良性病变患者纳入对照组,将其中102例甲状腺乳头状癌患者纳入观察组。对比两组患者CK19、MC、TPO、CD56的检测结果,总结CK19、MC、TPO、CD56联合检测诊断甲状腺乳头状癌的效能。结果:观察组CK19、MC的阳性检出率均高于对照组,TPO、CD56的阳性检出率均低于对照组,差异有统计学差异(P<0.05)。观察组CK19、MC、TPO、CD56联合检测的阳性检出率高于对照组,差异有统计学差异(P<0.05)。CK19、MC、TPO、CD56联合检测诊断甲状腺乳头状癌的灵敏度、特异度、准确率均显著高于四项指标单独检测。结论:将CK19、MC、TPO、CD56联合应用到甲状腺乳头状癌患者的病理诊断中,能提升诊断的准确率,值得推广应用。
出处 《当代医药论丛》 2022年第20期144-147,共4页
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