摘要
目的:研究调心理乱汤治疗紊脉型郁证的临床疗效及安全性。方法:采用非劣效性试验,使用随机数字表法将30例患者分为试验组16例、对照组14例,分别给予调心理乱汤和归脾汤,每日1剂,服药2周。观察比较两组患者的症状自评量表(Symptom Checklist-90,SCL-90)评分、汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)评分和中医症状量表评分变化以及检查结果,以上指标于治疗前后各评价1次。结果:试验组相较于对照组,总有效率较高;组内比较,治疗前后两组患者的SCL-90评分、HAMD评分、HAMA评分、中医症状量表评分均下降;组间比较,差异均无统计学意义(P>0.05)。结论:调心理乱汤治疗紊脉型郁证,对患者SCL-90评分、HAMD评分、HAMA评分、中医症状量表评分多有改善且安全性较高,有临床推广应用的价值。
Objective:To study the clinical efficacy and safety of the Tiaoxin Liluan decoction(调心理乱汤)on depression of turbulence pulse type.Methods:In the non-inferiority test,a total of 30 patients were divided into the experimental group(with 16 cases)and the control group(with 14 cases)by random number table method.The changes of symptom checklist 90(SCL-90)score,Hamilton depression scale(HAMD)score,Hamilton anxiety scale(HAMA)score and TCM symptom scale score and examination results were observed and compared between two groups.The above indicators were evaluated before and after treatment.Results:The total efficiency in the experimental group was higher than that in the control group.Within both groups,the scores of SCL-90,HAMD,HAMA and TCM symptom scale were decreased after treatment.There was no statistical significance between groups(P>0.05).Conclusion:The Tiaoxin Liluan decoction can ameliorate SCL-90,HAMD,HAMA and TCM symptom scale scores in the treatment of depression of turbulence pulse type,with high safety and clinical application value.
出处
《中医临床研究》
2022年第29期89-92,共4页
Clinical Journal Of Chinese Medicine
基金
山西中医药大学2020年度山西教育厅项目(2020L0449):基于人工智能的中医内科诊疗系统的设计研究
山西中医药大学2020年度科技创新能力培育计划中医学术流派传承工作室建设项目(2020PYLP-05):三部六病学术流派传承工作室。
关键词
调心理乱汤
归脾汤
紊脉型郁证
The Tiaoxin Liluan decoction
The Guipi decoction
Depression of turbulence pulse type