中药方剂贴敷联合西药治疗急性胆囊炎的临床对照研究

A clinical control study on the treatment of acute cholecystitis by TCM medicine external application plus Western medicine

目的:考察中药组方治疗急性胆囊炎临床疗效和对炎性因子水平的影响。方法:将高密市人民医院2018年12月-2020年8月就诊的急性胆囊炎患者124例采用随机数字表法分组。治疗组、对照组患者全部给予止痛、解痉、抗感染等西医对症基础治疗,治疗组在此基础上采用中西医结合治疗。考察患者肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)、C反应蛋白(C-reactive Protein,CRP)、白细胞介素-6(Interleukin-6,IL-6)等炎性因子水平和血常规白细胞计数(White Blood Cell,WBC)、总胆红素(Total Bilirubin,TBIL)水平。结果:治疗组总有效率为91.9%(57/62),对照组总有效率为77.4%(48/62)。治疗后,治疗组患者WBC、TBIL、TNFα、CRP、IL6等指标的水平均优于对照组(P<0.05)。结论:急性胆囊炎的中西医结合治疗效果肯定。

Objective:To investigate the clinical efficacy of TCM on acute cholecystitis and its influence on the level of inflammatory factors.Methods:A total of 124 patients with acute cholecystitis from December 2018 to August 2020 were randomly divided into two groups.All patients were given Western medicine symptomatic basic treatment such as pain relief,spasmolysis and anti infection,while the treatment group was treated in the integrative medicine.The levels of tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6)and other inflammatory factors,as well as blood routine WBC and total bilirubin(TBIL)were measured.Results:The total effective rate was 91.9%in the treatment group and 77.4%in the control group.After treatment,WBC,TBIL,TNF-α,CRP,IL-6 and other indicators in the treatment group were better than those in the control group(P<0.05).Conclusion:The effect of the integrative medicine on acute cholecystitis is positive.