硝普钠联合系统化急救护理干预对高血压合并急性心力衰竭患者血流动力学及血清心肌肌钙蛋白Ⅰ、高敏C反应蛋白的影响

Effects of Sodium Nitroprusside Combined with Systematic Emergency Nursing Intervention on Hemodynamics and Serum Cardiac Troponin Ⅰ and High-sensitivity C-reactive Protein in Patients with Hypertension and Acute Heart Failure

目的:探讨硝普钠联合系统化急救护理干预对高血压合并急性心力衰竭(AHF)患者的应用价值。方法:选取2019年8月-2020年10月郑州市第二人民医院收治的92例高血压合并AHF患者作为研究对象,按入院时间分为实验组(n=46)与对照组(n=46)。两组患者均采用硝普钠治疗,对照组采用常规护理,实验组在对照组基础上采用系统化急救护理干预。对比两组患者干预前后血流动力学、血清心肌肌钙蛋白Ⅰ(cTnI)、高敏C反应蛋白(hs-CRP)、不良反应发生率、护理满意度及生活质量。结果:干预后,实验组舒张压、心率均较对照组低,差异有统计学意义(t=12.950、9.979,P<0.05);干预后,实验组血清cTnI、hs-CRP均较对照组低,差异有统计学意义(t=28.578、45.454,P<0.05);干预后,实验组LVEDD水平较对照组低,LVEF水平较对照组高,差异有统计学意义(t=6.369、7.400,P<0.05);实验组不良反应发生率较对照组低,差异有统计学意义(χ^(2)=4.434,P<0.05);实验组护理满意度较对照组高,差异有统计学意义(χ^(2)=6.133,P<0.05);干预后,实验组情绪角色、躯体功能评分较对照组高,差异有统计学意义(χ^(2)=13.232、17.149,P<0.05)。结论:硝普钠联合系统化急救护理干预治疗高血压合并AHF患者,可改善血流动力学,减轻炎性反应和心肌损伤,并能降低不良反应发生率,提高护理满意度,改善生活质量。

Objective:To explore the application value of sodium nitroprusside combined with systematic emergency nursing intervention in hypertensive patients with acute heart failure(AHF).Methods:A total of 92 patients with hypertension and AHF admitted to the hospital from August 2019 to October 2020 were selected as the research objects,and divided into experimental group and control group according to the time of admission,with 46 cases in each group.Both groups were treated with sodium nitroprusside,the control group was treated with routine nursing,and the experimental group was treated with systematic emergency nursing intervention on the basis of the control group.The hemodynamics,serum cardiac troponin I(cTnI),high-sensitivity C-reactive protein(hs-CRP),incidence of adverse reactions,nursing satisfaction and quality of life were compared between the two groups before and after intervention.Results:After the intervention,the diastolic blood pressure and heart rate of the experimental group were lower than those of the control group,and the difference was statistically significant(t=12.950,9.979,P<0.05).After intervention,serum cTnI and hs-CRP in the experimental group were lower than those in the control group,and the difference was statistically significant(t=28.578,45.454,P<0.05).After intervention,the level of LVEDD in the experimental group was lower than that in the control group,and the level of LVEF was higher than that in the control group,and the difference was statistically significant(t=6.369,7.400,P<0.05).The incidence of adverse reactions in the experimental group was lower than that in the control group,and the difference was statistically significant(χ^(2)=4.434,P<0.05).The nursing satisfaction of the experimental group was higher than that of the control group,and the difference was statistically significant(χ^(2)=6.133,P<0.05).After the intervention,the emotional role and physical function scores of the experimental group were higher than those of the control group,and the difference was statistically significant(χ^(2)=13.232,17.149,P<0.05).Conclusion:Sodium nitroprusside combined with systematic emergency nursing intervention in the treatment of hypertension and AHF patients can improve hemodynamics,reduce inflammatory response and myocardial injury,reduce the incidence of adverse reactions,improve nursing satisfaction,and improve quality of life.