克氏棒杆菌与肉芽肿性乳腺炎相关性的研究进展

Research progress on the correlation between Corynebacterium kroppenstedtii and granulomatous mastitis

克氏棒杆菌是棒杆菌属的一员,基因组序列分析显示其具有亲脂性(需要脂质)的特点。克氏棒杆菌的临床分离株几乎均来自女性患者,且主要分离自乳腺脓肿和肉芽肿性乳腺炎(granulomatous mastitis,GM)患者的病变乳房组织样本,但其在乳腺病理中的作用尚不明确。本文对克氏棒杆菌与GM相关性的研究进展进行了综述。

Corynebacterium kroppenstedtii(C.kroppenstedtii)is a member of the genus Corynebacterium.Genome sequence analysis of the C.kroppenstedtii type strain has revealed a lipophilic(lipid-requiring)lifestyle.The clinical isolates of C.kroppenstedtii have been obtained almost exclusively from female patients,and mainly from the diseased breast tissue samples of the patients with breast abscess and granulomatous mastitis(GM).However,the role of C.kroppenstedtii in breast pathologies remains unclear.This paper reviews the research progress on the correlation between C.kroppenstedtii and granulomatous mastitis.