临床神经阻滞镇痛单纯局麻药镇痛和局麻药联合地佐辛镇痛效果的对比分析

Comparative Analysis of Analgesic Effects of Clinical Nerve Block Anal⁃gesia with Local Anesthetics Alone and Local Anesthetics Combined with Dizocine

目的探讨对神经阻滞镇痛患者分别采用单纯局麻药镇痛以及局麻药+地佐辛完成镇痛后获得临床效果。方法随机选取2018年1月—2021年12月收治的60例神经阻滞镇痛患者进行麻醉研究。随机分为常规组(采用罗哌卡因单独注射完成局麻镇痛)和研究组(在常规组基础上添加地佐辛药物完成镇痛),各30例。比较两组患者镇痛效果、麻醉效果、不良反应总发生率。结果研究组术前15 min、术中30 min、术中60 min、术后1 h、术后12 h、术后24 h镇痛效果评分均低于常规组,差异有统计学意义(P<0.05);研究组痛觉消失时间(18.15±2.46)min、麻醉起效时间(2.99±0.39)min、镇痛持续时间(12.15±2.19)h均优于常规组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论单纯局麻药+地佐辛药物联合应用,可显著提高神经阻滞镇痛患者镇痛效果,缩短痛觉消失时间、麻醉起效时间,有效延长镇痛持续时间,有效改善患者预后。

Objective To investigate the clinical effect of local anesthetic alone and local anesthetic+dezocine in pa‐tients with nerve block analgesia.Methods A total of 60 patients with nerve block analgesia admitted from January 2018 to December 2021 were randomly selected for anesthesia research.They were randomly divided into routine group(using ropivacaine alone to complete local anesthesia analgesia)and study group(adding dezocine drug to com‐plete analgesia on the basis of routine group),30 cases in each group.The analgesic effect,anesthesia effect and the total incidence of adverse reactions were compared between the two groups.Results The analgesic effect scores at 15 minutes before operation,30 minutes during operation,60 minutes during operation,1 hour after operation,12 hours after operation,and 24 hours after operation in the study group were lower than those in the routine group,and the differences were statistically significant(P<0.05).The pain disappearance time(18.15±2.46)min,the onset time of anesthesia(2.99±0.39)min,and the analgesia duration(12.15±2.19)h in the study group were all better than those in the routine group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combined applica‐tion of simple local anesthetic and dezocine can significantly improve the analgesic effect in patients with nerve block analgesia,and shorten the time of pain disappearance and the onset of anesthesia,effectively prolong the dura‐tion of analgesia and effectively improve the prognosis of patients.