富血小板纤维蛋白应用于恒牙根尖屏障术中修复骨缺损的临床效果

Clinical effect of platelet-rich fibrin in repairing bone defects during apical barrier surgery of permanent teeth

目的探讨富血小板纤维蛋白(PRF)在恒牙根尖屏障术中修复骨缺损的应用价值。方法选取2018年1月至2021年8月在齐齐哈尔医学院附属第五医院大庆龙南医院口腔科就诊的成人开放性慢性根尖周炎(CAP)患者60例作为研究对象,按照随机数表法分为观察组(30例)和对照组(30例),其中对照组患者采用iRoot-BP行根尖屏障术,观察组患者采用PRF制作根尖外屏障,并行根尖屏障术。术后比较两组影像学结果、疗效、操作时间及满意度。结果观察组14例完全愈合,16例不完全愈合;对照组9例完全愈合,13例不完全愈合,6例不确定愈合,2例不满意愈合,两组比较差异有统计学意义(P<0.05);经过治疗,观察组患者全部成功,对照组失败6例,观察组临床疗效优于对照组,差异有统计学意义(P<0.05);观察组术后6个月患者咀嚼功能、语言功能、美观度、舒适度评分高于对照组,差异有统计学意义(P<0.05);观察组的操作时间短于对照组,差异有统计学意义(P<0.05)。结论采用PRF应用于恒牙根尖屏障术中治疗开放性CAP,能够有效促进根尖骨缺损的修复,缩短术中操作时间,且能够获得较高的满意度,值得临床推广应用。

Objective To explore the application value of platelet-rich fibrin(PRF)in repairing bone defects during apical barrier surgery of permanent teeth.Methods A total of 60 adult patients with open chronic apical periodontitis(CAP)who were treated in the Department of Stomatology of Daqing Long Nan Hospital,the Fifth Affiliated Hospital of Qiqihar Medical University from January 2018 to August 2021,were selected as the study objects and divided into the observation group(30 cases)and the control group(30 cases)by the random number table method.Patients in the control group underwent apical barrier surgery with iRoot-BP,while patients in the observation group underwent apical barrier surgery with PRF.The imaging results,efficacy,operation time and satisfaction of the two groups were compared.Results In the observation group,14 cases were healed completely,16 cases were healed incompletely;In the control group,9 cases were healed completely,13 cases were healed incompletely,6 cases were healed indefinitely,2 cases were healed unsatisfactorily.There was statistically significant difference between the two groups(P<0.05).After treatment,all cases in the observation group were successful,while 6 cases in the control group failed.It showed that the clinical efficacy of the observation group was better than that of the control group,with statistically significant difference(P<0.05).The scores of chewing function,language function,aesthetics and comfort of patients in the observation group were higher than those in the control group 6 months after surgery,with statistically significant differences(P<0.05).The operation time of patients in the observation group was shorter than that in the control group,with statistically significant difference(P<0.05).Conclusion The application of PRF in the treatment of open CAP in the apical barrier surgery of permanent teeth can effectively promote the repair of apical bone defects,shorten the operation time,and obtain high satisfaction.Therefore,it is worthy of clinical promotion.