成年急性缺血性脑卒中患者衰弱现状及影响因素分析

Analysis of frailty status quo and influencing factors in adult patients with acute ischemic stroke

目的了解成年急性缺血性脑卒中(AIS)患者衰弱现状及其影响因素。方法采用横断面调查法,选取在某三甲医院住院的AIS患者215例,基于衰弱指数(FI)评估患者衰弱现状,影响因素分析采用多元logistic回归分析。结果最终纳入211例AIS患者,其中衰弱前期、衰弱分别占81例(38.39%)、81例(38.39%)。Logistic回归分析结果表明:年龄[OR=0.95,95%CI(0.90,0.99)]、高血压[OR=4.22,95%CI(1.57,11.32)]、糖尿病[OR=3.34,95%CI(1.10,10.18)]、血清血红蛋白[OR=1.03,95%CI(1.00,1.05)]、TOAST分型[心源性脑栓塞OR=0.02,95%CI(0.00,0.48)和小动脉闭塞性脑卒中或腔隙性脑卒中OR=0.10,95%CI(0.02,0.52)]、肌少症[OR=5.74,95%CI(1.90,17.37)]是成年AIS患者衰弱的影响因素。结论年龄、高血压、糖尿病、脑卒中分型(心源性脑栓塞、小动脉闭塞性脑卒中或腔隙性脑卒中)、血清血红蛋白水平和肌少症均是成年AIS患者衰弱的影响因素。

Objective To understand the current status of frailty in the patients with acute ischemic stroke(AIS),and to analyze its influencing factors.Methods A total of 215 patients with AIS hospitalized in a class A tertiary hospital were selected by using the cross sectional investigation method,and the frailty status quo of the patients was assessed based on the frailty index(FI).The multivariate logistic regression analysis was used to analyze the influencing factors.Results Finally,211 cases of AIS were included,including 81 cases of prefrailty and frailty,accounting for 38.39%and 38.39%,respectively.The logistic regression analysis results showed that:age[OR=0.95,95%CI(0.90,0.99)],hypertension[OR=4.22,95%CI(1.57,11.32)],diabetes[OR=3.34,95%CI(1.1,10.18)],serum hemoglobin level[OR=1.03,95%CI(1.00,1.05)],and TOAST type cardiogenic embolism[OR=0.02,95%CI(0.00,0.48)]arteriolar occlusive stroke or lacunar stroke [OR=0.10,95%CI(0.02,0.52)]and sarcopenia[OR=5.74,95%CI(1.90,17.37)]were the influencing factors of frailty in adult patients with AIS.Conclusion Age,hypertension,diabetes,stroke type(cardiac embolism,arteriolar occlusive stroke or lacunar stroke),serum hemoglobin level and sarcopenia are the influencing factors of frailty in the patients with AIS.