能谱CT联合形态学特征对甲状腺结节的诊断意义

Diagnostic significance of combined energy spectrum CT and morphological characteristics in thyroid nodules

目的探讨联合能谱CT和形态学特征对甲状腺结节的诊断价值。方法分析126例患者140个甲状腺结节的临床、病理、影像学资料。结果良恶性病灶在形态学特征方面差异有统计学意义(P<0.01)。在诊断恶性肿瘤时静脉期各项参数的联合诊断效能值较高,其阈值分别为碘浓度(IC)<37.08×100 mg/L、标准化碘浓度(NIC)<0.79和能谱曲线斜率(λ_(HU))<4.45。综合能谱CT参数IC、NIC、λ_(HU)及形态学特征对甲状腺癌的诊断效能均高于单独的形态学特征或静脉期各项参数的诊断效能。结论能谱CT联合形态学特征能提高甲状腺结节良恶性的诊断效能。

Objective To study the significance of combined energy spectrum CT and morphological characteristics in thyroid nodules.Methods Clinical,pathological and imaging data of 126 patients(140 thyroid nodules)were analyzed.Results There was significant difference in morphological characteristics between benign and malignant thyroid nodules(P<0.01).The diagnostic efficiency of venous phase parameters was higher for malignant thyroid nodules,and thresholds of iodine concentration(IC),normalized iodine concentration(NIC)and slope of energy spectrum curve(λ_(HU))were<37.08×100 mg/L,0.79 and 4.45,respectively.Combined application of energy spectrum parameters(IC,NIC,λ_(HU))and morphological features was superior to single morphological features or venous phase parameters in the diagnosis of thyroid cancer.Conclusion Combined energy spectrum CT and morphological characteristics can improve the diagnostic efficiency for benign and malignant thyroid nodules.