乙酰丙酮生产技术分析

Acetyl acetone production technology analysis

乙酰丙酮作为一种重要的原辅材料,在医药行业、兽药生产、饲料添加剂等方面都有使用,它还是重要的催化剂,可以用于有机化工中间体的生产。目前,我国的乙酰丙酮主要用来生产磺胺类药物,同时,我国是磺胺类药物的生产和出口大国,对原辅材料乙酰丙酮的需求量也巨大。生产乙酰丙酮一般采用乙烯酮-丙酮路线,该工艺较为成熟,已在国内外广泛投入工业生产。但是该方法存在明显的缺点,例如工艺流程复杂,产品纯度较低,设备需要投资大,生产能耗高,会产生副产品等,导致该生产路线已经难以满足绿色化学的发展要求。因此,对该路线进行升级改进以弥补该方法在生产乙酰丙酮过程中的能源资源浪费,实现更加高效、环保的合成路线,是未来乙酰丙酮生产的重要方向。本文介绍了乙酰丙酮工艺技术的来源,以及国内外不同生产技术的原理及特点。

Acetyl acetone,as an important raw and auxiliary material,is used in the pharmaceutical industry,veterinary medicine production,feed additives and other aspects,it is also an important catalyst,can be used in the middle of the production stage of organic chemical industry.At present,China's acetyl acetone is mainly used to produce sulfa drugs.At the same time,China is a big country in the production and export of sulfa drugs,and the demand for raw and auxiliary materials acetyl acetone is correspondingly huge.The production of acetyl acetone generally adopts the route of vinyl ketone,which is relatively mature and has been widely used in industrial production at home and abroad.However,this method has obvious disadvantages,such as complex process,low product purity,high equipment investment,high production energy consumption,and by-products,which lead to the production route has been difficult to meet the development requirements of green chemistry.Therefore,it is an important direction of acetyl acetone production in the future to find other synthetic process routes to make up for the waste of energy resources in the process of acetyl acetone production,and to achieve a more efficient and environmentally friendly synthetic route.This paper describes the source of acetyl acetone technology and the principle and characteristics of different production technology at home and abroad.