摘要
目的探讨动脉粥样硬化患者经皮冠状动脉介入治疗(PCI)术后短期不良预后的危险因素。方法选择2019年1月至2021年6月于河南省直第三人民医院住院的动脉粥样硬化并行PCI的患者125例作为研究对象,随访患者短期不良预后的发生情况,并收集临床资料分析短期不良预后的危险因素。结果125例患者均成功完成PCI,手术时间为41~58 min,平均手术时间(50.12±2.65)min,术后随访发现,再发心绞痛6例、心肌梗死7例、心律失常6例、血运重建5例和心力衰竭7例,再发不良预后率为24.80%。根据预后情况分为预后不良组(n=31)和预后良好组(n=94),两组在性别、糖尿病、饮酒、独居、首次PCI及家族史比较,差异均无统计学意义(P>0.05);预后不良组年龄、合并高血压、高脂血症、吸烟史、冠状动脉(冠脉)病变支数多支、心功能分级均高于预后良好组,辅助用药、术前他汀类治疗比较均低于预后良好组,差异有统计学意义(P<0.05)。多因素非条件Logistic分析显示,年龄、高血压、高脂血症、辅助用药、饮酒、冠脉病变支数、心功能分级、术前他汀类治疗均为PCI术后短期不良预后的独立危险因素(P<0.05)。结论动脉粥样硬化患者PCI术后短期不良预后发生率较高,应重点关注危险因素并及时干预。
Objective To discuss the risk factors of short-term poor prognosis in patients with atherosclerosis(AS)after percutaneous coronary intervention(PCI).Methods AS patients undergone PCI(n=125)were chosen from the Third People’s Hospital of Henan Province from Jan.2019 to June 2021.The incidence of short-term poor prognosis was followed up,and clinical materials were collected for analyzing the risk factors of short-term poor prognosis in all patients.Results All 125 patients were received successfully PCI,and the operation time was from 41 min to 58 min[averagely(50.12±2.65)min].The results of postoperation follow-up showed that there were 6 cases of relapsed angina pectoris,7 cases of myocardial infarction,6 cases of arrhythmia,5 cases of revascularization and 7 cases of heart failure.The rate of relapsed poor prognosis was 24.80%.All patients were divided,according to their prognosis,into poor prognosis group(n=31)and good prognosis group(n=94).The differences in gender,diabetes,drinking,living alone,first-time PCI and family history had no statistical significance between 2 groups(P>0.05).The gender,hypertension,hyperlipidemia,smoking history,multi-vessel lesions of coronary artery and heart function classification were all higher,and adjuvant drugs and preoperative statin treatment were lower in poor prognosis than those in good prognosis(P<0.05).The results of multi-factor unconditional Logistic analysis showed that age,hypertension,hyperlipidemia,adjuvant drugs,drinking,diseased vessels of coronary artery,heart function classification and preoperative statin treatment were all independent risk factors of short-term poor prognosis after PCI(P<0.05).Conclusion The incidence rate of short-term poor prognosis after PCI is higher in AS patients,so risk factors should be paid more attention to and be intervened in time.
作者
李晶
常亚伟
张丹峰
张玉琴
丁怀兰
Li Jing;Chang Yawei;Zhang Danfeng;Zhang Yuqin;Ding Huailan(Department of Cardiology,Third People's Hospital of Henan Province,Zhengzhou 450000,China)
出处
《中国循证心血管医学杂志》
2022年第9期1133-1135,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
关键词
动脉粥样硬化
经皮冠状动脉介入
短期
不良预后
危险因素
Atherosclerosis
Percutaneous coronary intervention
Short period
Poor prognosis
Risk factors