甲状腺激素与不同阶段2型糖尿病肾病的相关性研究

Study on the Correlation Between Thyroid Hormone andDifferent Stages of Type 2 Diabetic Nephropathy

2型糖尿病肾病是导致终末期肾衰竭的主要原因,及时评估其病情进展,同时给予积极干预,是延迟并控制终末期肾病的重要方式。甲状腺激素作为内分泌领域常见指标,现已有研究证实,该指标与2型糖尿病肾病的发生发展存在密切相关。其中,糖尿病肾病进展是引起甲状腺激素变化的重要原因,而甲状腺激素异常是导致糖尿病肾病进展的独立危险因素。本文结合2型糖尿病肾病的分期标准,针对甲状腺激素与不同阶段2型糖尿病肾病的相关性作一综述,以期为临床诊治该病提供参考。

Type 2 diabetic nephropathy is the main cause of end-stage renal failure.Timely assessment of its progression and active intervention are important ways to delay and control end-stage renal disease.As a common index in the field of endocrine,thyroid hormone has been proved to be closely related to the occurrence and development of type 2 diabetic nephropathy.Among them,the progress of diabetic nephropathy is an important cause of thyroid hormone changes,and thyroid hormone abnormalities are independent risk factors leading to the progress of diabetic nephropathy.Based on the staging criteria of type 2 diabetic nephropathy,this paper reviews the correlation between thyroid hormone and type 2 diabetic nephropathy in different stages,in order to provide reference for clinical diagnosis and treatment of the disease.