急性进展性后循环脑梗死血管因素研究进展

Research Progress of Vascular Factors in Acute Progressive Posterior Circulation Cerebral Infarction

进展性脑梗死是临床常见疾病,具有发病率、病死率以及致残率高的特点。急性进展性脑梗死分为前循环脑梗死和后循环脑梗死,与前循环脑梗死比较,进展性后循环脑梗死致残率、死亡率更加显著,严重威胁患者的健康安全。目前,关于急性进展性后循环脑梗死的发病机制尚未完全明确,加之病理生理相关因素复杂,临床治疗难度较大。血压改变会影响血流动力学,改变缺血脑组织灌注,从而使脑梗死加剧、恶化。因此,血管因素在急性进展性后循环脑梗死中发挥重要的作用。本文对急性进展性后循环脑梗死相关血管因素研究进展进行综述,以期为临床治疗急性进展性后循环脑梗死提供新的方向。

Progressive cerebral infarction is a common clinical disease with high morbidity,mortality and disability.Acute progressive cerebral infarction is divided into anterior circulation cerebral infarction and posterior circulation cerebral infarction.Compared with anterior circulation cerebral infarction,the disability rate and mortality of progressive posterior circulation cerebral infarction are more significant,which seriously threatens the health and safety of patients.At present,the pathogenesis of acute progressive posterior circulation cerebral infarction is not completely clear,and the pathophysiological factors are complex,so the clinical treatment is difficult.Changes in blood pressure will affect hemodynamics and change the perfusion of ischemic brain tissue,thus aggravating and worsening cerebral infarction.Therefore,vascular factors play an important role in acute progressive posterior circulation cerebral infarction.This article reviews the research progress of vascular factors related to acute progressive posterior circulation cerebral infarction,in order to provide a new direction for clinical treatment of acute progressive posterior circulation cerebral infarction.