内蒙古自治区吸毒人群丙型肝炎和梅毒感染分析

Prevalence of hepatitis C and syphilis infections among drug users in Inner Mongolia Autonomous Region

目的了解内蒙古自治区吸毒人群丙型肝炎病毒(HCV)和梅毒感染状况。方法通过国家艾滋病哨点监测数据管理系统收集2021年内蒙古自治区5个国家级艾滋病监测哨点吸毒人群资料,分析性行为、毒品使用、HIV检测和接受行为干预情况;采用多因素logistic回归模型分析吸毒人群HCV和梅毒感染的影响因素。结果监测吸毒人员2019人,年龄为(43.32±9.88)岁。男性1958人,占96.98%。本地户籍1830人,占90.64%。在婚/同居1038人,占51.41%。初中及以下学历1410人,占69.84%。汉族1884人,占93.36%。使用传统毒品1605人,占79.49%;使用新型毒品283人,占14.02%;使用混合毒品131人,占6.49%。注射吸毒340人,占16.84%,其中共用针具41人,占12.06%。近1年有商业性行为460人,占22.78%。HCV阳性477例,阳性率为23.63%;梅毒阳性77例,阳性率为3.81%;未检测发现HIV阳性。多因素logistic回归分析结果显示,年龄(40岁~,OR=3.747,95%CI:2.161~6.497;≥50岁,OR=5.302,95%CI:3.064~9.177)、本地户籍(OR=3.409,95%CI:1.935~6.008)、使用传统毒品(OR=1.477,95%CI:1.035~2.108)和注射吸毒(OR=2.700,95%CI:2.067~3.527)的吸毒人员HCV感染风险升高;离异/丧偶(OR=3.413,95%CI:1.463~7.962)和外地户籍(OR=2.404,95%CI:1.304~4.433)的吸毒人员梅毒感染风险升高。结论内蒙古自治区哨点监测吸毒人群以中年男性为主,HCV和梅毒感染与年龄、户籍、婚姻状况、使用毒品类型、吸毒方式有关。

Objective To investigate the prevalence of hepatitis C virus(HCV)and syphilis among drug users(DUs)in Inner Mongolia Autonomous Region.Methods DUs'epidemiological data were collected from 5 national AIDS surveil⁃lance sentinels in Inner Mongolia Autonomous Region in 2021 through the National HIV/AIDS Sentinel Surveillance Da⁃ta Management System,and sexual behaviors,DU behaviors,HIV testing and behavioral interventions were descriptively analyzed.The factors affecting the HCV and syphilis infections were identified among DUs using a multivariable logistic regression model.Results A total of 2019 DUs were enrolled,with a mean age of(43.32±9.88)years.Among the par⁃ticipants,there were 1958 males(96.98%),1830 with local registered residence(90.64%),1038 with marriage/cohabi⁃tation(51.41%),1410 with an educational level of junior high school and above(69.84%),and 1884 with Han Ethnic⁃ity(93.36%).There were 1605 DUs with use of conventional drugs(79.49%),283 with use of new drugs(14.02%)and 131 with use of mixed drugs(6.49%),and there were 340 DUs with injection drug use(16.84%),including 41 that shared the needles(12.06%).There were 460 DUs with commercial sexual behaviors in the past year(22.78%).The percentage of HCV and syphilis positive was 23.63%and 3.81%,respectively,while no HIV positive case was de⁃tected.In addition,multivariable logistic regression analysis showed that age(40 years-,OR=3.747,95%CI:2.161-6.497;50 years and older,OR=5.302,95%CI:3.064-9.177),local registered residence(OR=3.409,95%CI:1.935-6.008),use of conventional drugs(OR=1.477,95%CI:1.035-2.108),and injection drugs(OR=2.700,95%CI:2.067-3.527)caused an increased risk of HCV infections among DUs,and divorced/widowed(OR=3.413,95%CI:1.463-7.962)and non-local registered DUs(OR=2.404,95%CI:1.304-4.433)had an increased risk of syphilis infections.Conclu⁃sions Middle-aged men are predominant DUs in national AIDS surveillance sentinels in Inner Mongolia Autonomous Region,and the prevalence of HCV and syphilis infections correlates with age,household registration,marital status,type of drugs used and route of drug use.