清醒俯卧位对新型冠状病毒肺炎气管插管率影响的meta分析

Effect of waking prone position on intubation rate in COVID-19 patients:a meta-analysis

目的:评估清醒俯卧位对新型冠状病毒肺炎(COVID-19)患者气管插管率的影响。方法:通过计算机检索中国知网(CNKI)、中国生物医学文献数据库(CBM)、Pub Med、Embase及Cochrane图书馆等数据库,检索时间为2019年12月至2021年8月。采用Rev Man 5.3软件进行meta分析。结果:本研究共纳入7篇研究,包含779例COVID-19患者,其中对照组500例,清醒俯卧位组279例。与对照组相比,清醒俯卧位组的气管插管率差异无统计学意义(RR=0.94,95%CI:0.77~1.15,P=0.57);清醒俯卧位组的病死率低于对照组(RR=0.56,95%CI:0.39~0.81,P=0.02)。结论:清醒俯卧位不能降低COVID-19患者的气管插管率,但可能有效降低其病死率。

Objective:To evaluate the effect of waking prone position on the intubation rate in COVID-19 patients.Methods:The databases of CNKI,CBM,Pub Med,Embase,and Cochrane Library,etc.were searched by computer from December 2019 to August 2021.Rev Man 5.3 software was used for meta-analysis.Results:A total of 7 studies including 779 COVID-19 patients were included in this study.Among them,there were 500 cases in the control group and 279 cases in the waking prone position group.Compared with the control group,the intubation rate of of the waking prone position group had no significant difference( RR =0.94,95% CI:0.77-1.15,P = 0.57).The case fatality of waking prone position group was lower than that of the control group( RR = 0.56,95% CI:0.39-0.81,P = 0.02).Conclusion:The waking prone position cannot reduce the intubation rate in COVID-19 patients,but it may effectively reduce the case fatality.