血清胆红素与尿酸检验诊断冠心病的临床价值探讨

Clinical value of serum bilirubin and uric acid test in the diagnosis of coronary heart disease

目的 研究采取血清胆红素与尿酸检验诊断冠心病的临床价值。方法 选择60例冠心病患者作为实验组,另选择同期60例体检健康者作为对照组。两组均进行血清胆红素与尿酸检验。对比两组血清总胆红素、直接胆红素、间接胆红素及尿酸水平,分析实验组的诊断准确率。结果 实验组血清总胆红素(10.95±1.56)μmol/L、直接胆红素(4.50±1.46)μmol/L、间接胆红素(5.30±1.36)μmol/L低于对照组的(15.50±1.45)、(6.10±1.53)、(10.50±1.45)μmol/L,尿酸(478.50±30.25)μmol/L高于对照组的(271.50±27.67)μmol/L,差异具有统计学意义(P<0.05)。60例冠心病患者,经血清胆红素、尿酸检验确诊58例,未确诊2例,诊断准确率为96.67%。结论 冠心病患者的血清胆红素与尿酸水平与健康者有一定的差异,采用血清胆红素与尿酸检验诊断冠心病的准确率较高,在临床诊断中有应用价值。

Objective To study the clinical value of serum bilirubin and uric acid test in the diagnosis of coronary heart disease.Methods A total of 60 patients with coronary heart disease were selected as the experimental group,and 60 healthy individuals who underwent physical examination during the same period were selected as the control group.Serum bilirubin and uric acid were tested in both groups.The levels of serum total bilirubin,direct bilirubin,indirect bilirubin and uric acid were compared between the two groups,and the diagnostic accuracy of the experimental group was analyzed.Results The serum total bilirubin(10.95±1.56)μmol/L,direct bilirubin(4.50±1.46)μmol/L and indirect bilirubin(5.30±1.36)μmol/L in the experimental group were lower than(15.50±1.45),(6.10±1.53)and(10.50±1.45)μmol/L in the control group;the uric acid(478.50±30.25)μmol/L in the experimental group was higher than(271.50±27.67)μmol/L in the control group;the differences were all statistically significant(P<0.05).Of the 60 patients with coronary heart disease,58 cases were confirmed by serum bilirubin and uric acid tests,and 2 cases were undiagnosed,with a diagnostic accuracy of 96.67%.Conclusion The serum bilirubin and uric acid levels of patients with coronary artery disease differ from those of healthy individuals.These two indicators has high diagnostic accuracy for coronary artery disease and contain application value in clinical diagnosis.