赖氨葡锌联合肠道活菌药物治疗肠炎的疗效探讨

Efficacy of compound lysine hydrochloride and zinc gluconate combined with viable intestinal bacteria in the treatment of enteritis

目的探讨赖氨葡锌联合肠道活菌药物治疗肠炎的疗效。方法90例肠炎患者,通过电脑随机分为实验组和对照组,每组45例。对照组患者采用肠道活菌药物治疗,实验组患者采用赖氨葡锌联合肠道活菌药物治疗。比较两组患者临床治疗效果、便血消失时间、腹痛缓解时间及临床症状评分。结果实验组患者临床治疗总有效率为95.56%,高于对照组的73.33%,差异具有统计学意义(P<0.05)。实验组患者的便血消失时间、腹痛缓解时间分别为(5.39±0.12)、(7.65±1.36)d,显著短于对照组患者的(5.89±0.19)、(8.59±1.11)d,差异具有统计学意义(P<0.05)。治疗3 d后,实验组患者腹泻评分、脓血便评分、腹痛评分分别为(2.03±1.45)、(1.34±1.02)、(1.32±1.03)分,均低于对照组的(2.88±2.06)、(1.94±1.43)、(1.95±1.45)分,差异具有统计学意义(P<0.05)。结论肠炎患者采用赖氨葡锌联合肠道活菌药物进行治疗,能够有效改善患者的临床症状,提升治疗效果,在临床上有着重要的应用意义。

Objective To discuss the efficacy of compound lysine hydrochloride and zinc gluconate combined with viable intestinal bacteria in the treatment of enteritis.Methods A total of 90 patients with enteritis were randomly divided into experimental group and control group by computer,with 45 cases in each group.Patients in the control group were treated with viable intestinal bacteria,and patients in the experimental group were treated with compound lysine hydrochloride and zinc gluconate combined with viable intestinal bacteria.The clinical effect,disappearance time of bloody stool,abdominal pain relief time and clinical symptom scores were compared between the two groups.Results The total effective rate of clinical treatment in the experimental group was 95.56%,which was higher than 73.33%in the control group,and the difference was statistically significant(P<0.05).The disappearance time of bloody stool and abdominal pain relief time in the experimental group were(5.39±0.12)and(7.65±1.36)d,which were significantly shorter than(5.89±0.19)and(8.59±1.11)d in the control group,and the differences were all statistically significant(P<0.05).After 3 d of treatment,the diarrhea score,pus and blood stool score,and abdominal pain score in the experimental group were(2.03±1.45),(1.34±1.02),and(1.32±1.03)points,which were lower than(2.88±2.06),(1.94±1.43),and(1.95±1.45)points in the control group,and the differences were all statistically significant(P<0.05).Conclusion Compound lysine hydrochloride and zinc gluconate combined with viable intestinal bacteria for enteritis patients can effectively improve the clinical symptoms of patients and improve the therapeutic effect,which has great clinical application significance.