ABVS检查联合SWE检查在乳腺癌诊断中的效能

Efficacy of ABVS combined with SWE in diagnosis of breast cancer

目的:观察自动乳腺全容积扫描(ABVS)检查联合剪切波弹性成像(SWE)检查在乳腺癌诊断中的效能。方法:选取2018年5月至2020年11月该院收治的82例高度疑似乳腺癌患者进行前瞻性研究。患者入院当天均行ABVS检查、SWE检查和穿刺活检病理检查,以穿刺活检病理结果为金标准,统计穿刺活检病理结果、ABVS和SWE单项及联合检查结果,比较ABVS和SWE单项及联合检查诊断乳腺癌的效能,并分析ABVS和SWE单项及联合检查结果与病理结果的一致性。结果:82例高度疑似乳腺癌患者共检出178个肿块,经穿刺活检病理结果显示,恶性肿块98个,检出率为55.06%;良性肿块80个,检出率为44.94%。ABVS检查联合SWE检查诊断乳腺癌的灵敏度、特异度、准确度、阳性预测值和阴性预测值均高于ABVS、SWE单项检查,SWE检查诊断乳腺癌的特异度、准确度和阳性预测值均高于ABVS,差异有统计学意义(P<0.05);ABVS检查与SWE检查的灵敏度和阴性预测值比较,差异无统计学意义(P>0.05);经Kappa检验结果显示,ABVS检查结果与穿刺活检病理结果的一致性一般(Kappa值=0.453,P<0.05);SWE检查结果与穿刺活检病理结果的一致性一般(Kappa值=0.672,P<0.05);联合检查结果与穿刺活检病理结果一致性良好(Kappa值=0.977,P<0.05)。结论:ABVS检查联合SWE检查诊断乳腺癌的效能高于两者单项检查。

Objective: To observe efficiency of automated breast volume scanning(ABVS) combined with shear wave elastography(SWE in diagnosis of breast cancer. Methods: A prospective study was conducted on 82 patients with highly suspected breast cancer admitted to the hospital from May 2018 to November 2020. All patients underwent ABVS examination, SWE examination and biopsy on the day of admission. Using the pathological results of biopsy as the gold standard, the results of single ABVS, single SWE and combined examination were statistically analyzed.Then, the efficacies of single ABVS, single SWE and combined examination in the diagnosis of breast cancer were compared. The consistency levels of single ABVS, single SWE and combined examination with the pathological results were calculated. Results: 178 masses were detected in 82patients with highly suspected breast cancer. The pathological results of puncture biopsy showed 98 malignant masses with a detection rate of 55.06%and 80 benign masses with the detection rate of 44.94%. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of ABVS combined with SWE in the diagnosis of breast cancer were higher than those of single ABVS and single SWE;the specificity, accuracy and positive predictive value of SWE in the diagnosis of breast cancer were higher than those of ABVS;and the differences were statistically significant(P0.05). The Kappa test showed that the consistency among ABVS examination results and puncture biopsy pathological results was general(Kappa value=0.453, P<0.05). The consistency between SWE examination results and biopsy pathological results was fair(Kappa value=0.672, P<0.05). The results of combined examination were in good agreement with those of puncture biopsy(Kappa value=0.977, P<0.05). Conclusions: The diagnostic efficiency of ABVS combined with SWE in the diagnosis of breast cancer is higher than those of single examinations.