人体口腔微生物运用于法医学个体识别的研究进展

Research Progress on the Application of Human Oral Microbiome in Forensic In⁃dividual Identification

口腔是仅次于肠道的人类第二大微生物库,定植了包括病毒、细菌、古核生物、真菌和原生动物等大量微生物。微生物细胞数量多、DNA稳定性好,并且个体具有独特的微生物群落,这些特点使得人类微生物群落有望成为新型法医学个体识别的生物标志。本文阐述了人体口腔微生物的特征和微生物分子标记,分析了微生物在法医学个体识别中的潜在应用价值,并综述了口腔微生物在此方面的研究进展。

The oral cavity is the second largest microbial bank in humans after the intestinal canal,colonizing a large number of microorganisms including viruses,bacteria,archaea,fungi and protozoa.The great number of microbial cells,good DNA stability,and individual has a unique microbial community,these characteristics make the human microbiome expected to become a new biomarker for forensic individual identification.This article describes the characteristics of human oral microorganisms and microbial molecular markers in detail,analyzes the potential application value of microorganisms in forensic individual identification,and reviews the research progress of human oral microorganisms in forensic individual identification.