不同TOAST分型急性缺血性脑卒中诊疗指南及专家共识解读

Interpretation of guidelines and expert consensus on diagnosis and treatment of acute ischemic stroke with different TOAST classifications

脑卒中是我国国民首位死亡原因,脑梗塞的主要发病机制是血管闭塞或血管栓塞致血流受限,引起脑组织缺血缺氧所致。根据栓子来源不同,有学者提出了TOAST病因学分型,目前针对缺血性卒中不同病因分型的急性期治疗,尤其是心源性栓塞型,国内外指南及专家共识有部分更新,本文以急性缺血性卒中(AIS)病因分型为主线,对近年来国内外更新的AIS指南及专家共识进行解读,以期为临床诊疗方案的选择提供参考,实现个体化最优治疗。

Stroke is the first cause of death in our country.The main pathogenesis of cerebral infarction is blood flow restriction caused by vascular occlusion or vascular embolism,resulting in cerebral ischemia and hypoxia.According to different sources of emboli,some scholars have proposed the TOAST etiological classification.At present,for the treatment of different etiological types of ischemic stroke in the acute phase,especially the cardioembolic type,domestic and foreign guidelines and expert consensus have been partially updated.The etiology classification of acute ischemic stroke is the main line,and the updated AIS guidelines and expert consensuses at home and abroad in recent years are interpreted in order to provide a reference for the selection of clinical diagnosis and treatment plans and achieve individualized optimal treatment.