下肢动脉硬化闭塞症患者术后复发情况及其影响因素

Postoperative Recurrence and Its Influencing Factors in Patients with Lower Extremity Arteriosclerosis Obliterans

目的观察下肢动脉硬化闭塞症(LEASO)患者术后复发情况,探讨影响LEASO患者术后复发的相关因素。方法选取河南省人民医院2018年10月至2020年2月收治的拟接受经皮腔内血管成形术治疗的102例LEASO患者。所有患者接受经皮腔内血管成形术治疗并接受为期2 a的随访,依据相关标准和影像学检查评估患者术后复发情况并进行分组;由研究人员询问并记录研究所需资料,将可能的影响因素纳入,分析可能导致LEASO患者术后复发的相关因素。结果102例LEASO患者术后2 a随访期间,有40例患者术后复发,复发率为39.22%。复发组长期吸烟、基础疾病、CHA2DS2-VASc评分和血清超敏C反应蛋白(hs-CRP)水平与未复发组比较,差异有统计学意义(P<0.05)。经logistic回归分析,结果显示,长期吸烟、合并基础疾病、CHA2DS2-VASc评分≥2分、血清hs-CRP水平过表达均是LEASO患者术后复发的影响因素(OR>1,P<0.05)。结论LEASO患者术后复发可能与长期吸烟、合并基础疾病、CHA2DS2-VASc评分≥2分、血清hs-CRP水平过表达等因素有关。

Objective To observe the postoperative recurrence of patients with lower extremity arteriosclerosis obliterans(LEASO)and explore the related factors affecting the postoperative recurrence of patients with LEASO.Methods A total of 102 patients with LEASO who were treated with percutaneous transluminal angioplasty in Henan Provincial People’s Hospital from October 2018 to February 2020 were selected.All patients were treated with percutaneous transluminal angioplasty and followed up for 2 years.The postoperative recurrence of patients was evaluated and grouped according to relevant standards and imaging examination.The data needed for the study were inquired and recorded by the researchers,and the possible influencing factors were included to analyze the related factors that might lead to postoperative recurrence in patients with LEASO.Results During the 2-year follow-up of 102 patients with LEASO,40 patients recurred,and the recurrence rate was 39.22%.There were significant differences in long-term smoking,underlying diseases,CHA2 DS2-VASc score and serum high sensitivity C-reactive protein(hs-CRP)levels between the recurrence group and the non-recurrence group(P<0.05).The results of logistic regression analysis showed that long-term smoking,complicated with basic diseases,CHA2 DS2-VASc score≥2 and overexpression of serum hs-CRP were the influencing factors of postoperative recurrence in patients with LEASO(OR>1,P<0.05).Conclusion The postoperative recurrence of patients with LEASO may be related to long-term smoking,basic diseases,CHA2 DS2-VASc score≥2,serum hs-CRP level overexpression and other factors.