彩色多普勒超声参数与BRVO合并ME患者病情程度、疗效的关系

The Relationship between Color Doppler Ultrasound Parameters and Disease Severity and Curative Effect in Patients with BRVO Combined with ME

本研究探讨彩色多普勒超声参数与视网膜分支静脉阻塞(BRVO)合并黄斑水肿(ME)患者病情程度、疗效的关系。选取86例BRVO合并ME患者作为研究组,另选取86例单纯BRVO患者作为对照组,均行彩色多普勒超声检查,分析视网膜中央动脉(CRA)及眼动脉(OA)彩色多普勒超声参数[收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)]与病情程度、疗效的关系。研究组CRA的EDV、PSV、RI低于对照组,且黄斑囊样水肿<弥漫性水肿<局限性水肿(P<0.05)。BRVO合并ME患者CRA的EDV、PSV、RI与病情程度均呈负相关(P<0.05)。治疗后,治疗有效患者CRA的EDV、PSV、RI高于无效患者,治疗前后差值高于无效患者(P<0.05)。EDV、PSV、RI差值联合预测BRVO合并ME疗效价值优于单一预测。可见彩色多普勒超声参数与BRVO合并ME患者病情程度、疗效密切相关,可指导临床诊治。

This study investigated the relationship between colour Doppler ultrasound parameters and the disease severity and outcome of patients with branch retinal vein occlusion(BRVO)combined with macular oedema(ME).Eighty-six patients with BRVO combined with ME were selected as the study group,and 86 patients with BRVO alone were included as the control group.Colour Doppler ultrasound examinations were performed to analyse the relationship between colour Doppler ultrasound parameters[peak systolic flow velocity(PSV),end-diastolic flow velocity(EDV)and resistance index(RI)]of the central retinal artery(CRA)and ophthalmic artery(OA)and the disease severity and its outcome.The results showed that the EDV,PSV and RI of CRA in the study group were lower than those of the control group,and macular cystoid edema<diffuse<restrictive(P<0.05).EDV,PSV and RI of CRA in patients with BRVO combined with ME were negatively correlated with the degree of disease(P<0.05).The EDV,PSV and RI of CRA were higher in effective patients than in ineffective patients after treatment,and the difference before and after treatment was higher than in ineffective patients(P<0.05).The combined value of EDV,PSV and RI difference predicted the efficacy of BRVO combined with ME better than the single prediction.It can be seen that colour Doppler ultrasound parameters are closely related to the disease severity and efficacy of BRVO combined with ME,which can guide clinical management.