变应性鼻炎非特异性免疫治疗的研究进展

Research progress on non-specific immunotherapy for allergic rhinitis

变应性鼻炎(AR)是耳鼻咽喉科的一种常见病、多发病,由于病程迁延、易反复发作,不仅会影响患者身心健康和生活质量,还会加重社会医疗卫生负担。尽管目前临床上AR的治疗手段繁多,部分患者仍然难以获得满意疗效。近年来,随着对AR发病机制的深入研究,非特异性免疫治疗逐渐受到临床医生们的重视。该文就近年来非特异性免疫治疗在AR上的临床应用进展做一综述,以期为更深入的研究提供参考。

Allergic rhinitis(AR)is a common and frequently-occurring disease in Department of Otorhinolaryngology.Due to the prolonged course of disease and frequent episodes,AR will not only affect physical and mental health and the quality of life of patients,but also increase the burden of social medical and health care.Currently,although multiple clinical interventions have been adopted to treat AR,some patients could not achieve satisfactory clinical efficacy.With the in-depth study on the pathogenesis of AR in recent years,non-specific immunotherapy has gradually attracted the attention of clinicians.In this article,recent research progress on clinical application of non-specific immunotherapy for AR was reviewed,aiming to provide references for further in-depth research.