早中期乳腺癌患者经改良根治术后生存质量相关影响因素研究

Factors associated with quality of survival after modified radical surgery for early to mid-stage breast cancer patients

目的:探讨早中期乳腺癌患者经改良根治术后生存质量相关影响因素研究。方法:将接受改良根治术治疗的107例早中期乳腺癌患者作为研究对象,对其进行问卷调查。应用乳腺癌患者生命质量测定量表(FACT-B)对患者进行生命质量评价,对患者术后生存质量影响因素的相关因素进行logistic分析。结果:所有患者FACT-B平均得分为(94.52±10.56)分。患者的年龄、文化程度、家庭收入、临床分期、乳腺癌家族史、术后放疗、上肢淋巴水肿、术后时间、家庭支持程度的FACT-B评分比较,差异有统计学意义(P<0.05);经logistic回归分析结果显示,以上因素为影响早中期乳腺癌患者经改良根治术后生存质量的相关影响因素(P<0.05)。结论:影响早中期乳腺癌患者的术后生存质量的相关因素复杂多样,应重点结合有效的干预措施,提高患者的术后生存质量,改善预后。

Objective:To investigate the factors influencing the quality of survival related to early to mid-stage breast cancer patients after modified radical surgery.Methods:One hundred and seven patients with early to mid-stage breast cancer treated by modified radical surgery were taken as the study population and questionnaires were administered to them.Their quality of life was evaluated by applying the Functional Assessment of Cancer Therapy-Breast(FACT-B)score,and the related factors affecting the quality of survival of the patients after surgery were logistically analyzed.Results:The mean FACT-B score for all patients was 94.52±10.56.There were statistically significant differences in the FACT-B scores of patients’age,education level,family income,clinical stage,family history of breast cancer,postoperative radiotherapy,upper limb lymphoedema,postoperative time,and degree of family support(P<0.05),and the results of logistic regression analysis showed that the above factors were the ones affecting the quality of survival of the patients(P<0.05).Conclusion:The factors affecting their postoperative quality of survival are complex and diverse,and effective interventions should be taken to improve their postoperative quality of survival and prognosis.