安慰针临床随机对照试验研究现状

Research status of placebo acupuncture clinical randomized controlled trials

回顾近年来国内安慰针临床随机对照试验研究,以总结安慰针的研究现状,分析安慰针设计、研究病种、疗效等。通过综述发现安慰针设计以不破皮钝头针为主;研究病种及以疼痛类疾病为主;安慰针对各类疾病均有一定疗效,除个别研究外试验组疗效均优于安慰针组。同时发现一些研究存在样本量较小、研究过程描述不够详细、缺乏标准化、未使用客观评价指标等缺陷。安慰针研究病种应选取能以客观指标评价疗效的疾病,再以疾病为导向,深入研究内在机制,并设计新型安慰针具,形成差异化研究方案,最终制定相应的标准,推动安慰针研究的进步。

Domestic randomized controlled clinical trial studies of placebo acupuncture in recent years were reviewed to summarize the research status,and analyze the design,disease type and efficacy of placebo acupuncture.Through the review,it is found that the design of placebo acupuncture was mainly blunt-ended needles that do not break the skin,the disease types studied were mainly painful diseases,the placebo needles had certain efficacy for all kinds of diseases,and the efficacy of the trial groups was better than the placebo needles except for some studies.Meanwhile,some studies were found to have small sample sizes,insufficient description of research process,lack of standardization,and failure to use objective evaluation indicators.It′s concluded that the disease types of placebo acupuncture studies should be selected to evaluate the efficacy by objective indicators,and then to study the intrinsic mechanism in depth with the disease as the guide,and to design a new type of placebo acupuncture device to form a differentiated research program,and finally to develop corresponding standards to promote the progress of placebo acupuncture studies.