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痛风急性发作期降尿酸治疗的研究进展 被引量:3

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摘要 痛风是嘌呤代谢紊乱和(或)尿酸排泄障碍而导致的一组异质性疾病,高尿酸血症和慢性炎症为其主要特征。传统观点认为痛风急性发作期应进行对症治疗,不宜过早开展降尿酸治疗,否则有加重痛风发作的风险,与近年来各大指南关于痛风急性发作期降尿酸治疗的指导意见存在矛盾。近年来的多项研究显示使用传统降尿酸药物进行急性期降尿酸治疗不会导致痛风发作程度、发作时间、发作风险的大幅波动,同时具有提高患者依从性、尽早使血尿酸达标的优势。但新型降尿酸药物在痛风急性发作期应用的研究相对缺失。本文就痛风急性发作期降尿酸治疗的研究进展进行综述,为临床治疗提供参考。
出处 《中国现代医生》 2022年第31期127-130,135,共5页 China Modern Doctor
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