生物质碳点荧光材料在生物医药领域中的应用

Application of Biomass Carbon Dot Fluorescence Materials in Biomedical Field

荧光材料由于具有特殊的光学性质,在生物医学、生物成像和荧光传感等相关领域有广泛的应用。与传统的荧光剂相比,纳米荧光材料具有稳定性好、荧光强度高等优点。然而,传统的荧光纳米材料通常含有重金属,使其在生物医药领域中的应用受到限制。生物质荧光碳点作为一种新型的荧光碳纳米材料,因具有优异的生物相容性、化学惰性、荧光可调节性,在生物医药、生物传感、荧光成像等多个领域展现出应用潜力。但是,目前生物质碳点应用于生物医药领域的综述文献相对较少。因此,本文总结了不同天然产物制备碳点的绿色合成方法,对碳点的荧光机理进行了分析和归纳,重点阐述了碳点在生物传感、生物成像、药物载体、生物抗菌剂等生物医药领域的应用研究,讨论了存在的问题,并对碳点在该领域的发展方向进行了展望。

Due to its special optical properties, fluorescent materials have been widely used in biomedicine, biological imaging, fluorescence sensing and other related fields. Compared with traditional fluorescent agents, nano-fluorescent materials have the advantages of good stability and high fluorescence intensity. However, traditional semiconductor nano-fluorescent materials often contain heavy metals, which limits their application in biomedical fields. As a new type of fluorescent carbon nanomaterials, biomass fluorescent carbon dots(CDs) have some favorable characteristics such as biocompatibility, chemical inertness and fluorescence regulation, which have potential applications in biomedicine, biosensor, fluorescence imaging and other fields. At present, there are relatively few studies on the application of biomass CDs in biomedicine field. Therefore, this article summarized the green synthesis methods of different natural products to prepare CDs, and analyzed the fluorescence mechanism of CDs. It focused on the application of CDs in biomedical fields such as biosensors, biological imaging, drug carriers and biological antibacterial agents, discussed the existing problems, and looked forward to its future development direction in this field.