临床药师干预对2型糖尿病患者用药依从性及有效性的影响研究

Effect of Clinical Pharmacist Intervention on Medication Compliance and Effectiveness of Type 2 Diabetes Patients

目的研究临床药师参与的药学服务对2型糖尿病患者用药安全性和有效性的影响。方法选取上海市青浦区朱家角人民医院2019年7月至2022年6月本院2型糖尿病患者住院例数共计200例,以随机数字表法分为观察组(100例)和对照组(100例)。观察组患者接受规范化的抗糖尿病相关药学服务,对照组患者仅接受普通的药学服务。对比分析两组患者的基本信息、血糖控制水平、用药偏差、服药依从性、住院总费用、药品不良事件及就医满意度。结果基本信息结果显示,两组在性别、BMI、年龄、糖尿病病程、居住地、教育水平、平时血糖控制、肾功能、血脂、高血压、并发症、抗菌药物使用方面比较无显著性差异(P>0.05),而两组在就业状态、不良反应、肝功能、带药情况、出院情况、保险情况方面比较差异有显著性(P<0.05)。血糖水平与住院指标结果显示,两组在晚餐后血糖、住院天数、住院总费用、西药费用方面比较,无显著性差异(P>0.05);观察组空腹血糖、餐后2 h血糖、睡前血糖水平明显低于对照组,差异显著(P<0.05)。口服降糖药的认知情况结果显示,干预后观察组患者对口服降糖药的正确认知及使用情况明显好于对照组(P<0.05)。结论临床药师的参与有利于2型糖尿病患者合理用药,有助于稳定患者血糖水平,降低医疗费用,提高患者用药的安全性和有效性。

Objective To study the effect of clinical pharmacists'participation in pharmaceutical care on the safety and effectiveness of medication in patients with type 2 diabetes.Methods 200 inpatients with diabetes in Zhujiajiao People's Hospital of Qingpu District from July 2019 to June 2022 were randomly divided into observation group(100 cases)and control group(100 cases).The patients in the observation group received standardized anti diabetes related pharmaceutical care,and the patients in the control group received general lifestyle education.The main indicators of the study were the analysis of patients'basic information,blood sugar control level,medication deviation,medication compliance,total hospitalization expenses,adverse drug events and medical satisfaction.Results The results of this information showed that there was no significant difference between the two groups in gender,BMI,age,course of diabetes,place of residence,education level,usual blood glucose control,renal function,blood lipids,hypertension,complications,and antibacterial drug use(P>0.05),while there were significant differences between the two groups in employment status,adverse reactions,liver function,drug use,hospital discharge,and insurance status(P<0.05).The results of blood glucose level and hospitalization index showed that there was no significant difference between the two groups in terms of blood glucose,length of hospitalization,total hospitalization cost and western drug cost after dinner(P>0.05),while the fasting blood glucose,postprandial blood glucose and bedtime blood glucose level in the observation group were significantly lower than those in the control group(P<0.05).The cognitive results of oral hypoglycemic drugs showed that the correct cognition and use of oral hypoglycemic drugs in the observation group after intervention were significantly better than those in the control group(P<0.05).Conclusion The participation of clinical pharmacists is beneficial to the rational use of drugs in patients with type 2 diabetes,helps to stabilize the blood sugar level of patients,reduce medical expenses,and improve the safety and effectiveness of medication.