甲状腺腺叶切除术对甲状腺结节患者甲状腺激素水平的影响分析

Effect of Thyroid Gland Lobectomy on Thyroid Hormone Levels in Patients with Thyroid Nodules

目的分析对甲状腺结节患者甲状腺腺叶切除术治疗后甲状腺激素水平变化情况和影响因素。方法选择本院2017年12月至2019年6月收治的甲状腺结节患者84例作为研究组,按照手术术式的不同均分为两组各42例,即接受甲状腺全切除术的对照组与接受甲状腺腺叶切除术的观察组,比较两组的临床指标、甲状腺激素水平及并发症。结果观察组的手术、下床活动及住院的时间均短于对照组,手术出血量少于对照组(P<0.05);术前两组患者的甲状腺激素水平无明显差异(P>0.05),观察组在术后15 d的FT_(4)、FT_(3)、TSH、T_(3)、T_(4)水平同对照组相比改善明显(P<0.05),而在术后1个月两组患者的FT_(4)、FT_(3)、TSH、T_(3)、T_(4)水平无明显差异(P>0.05);观察组的术后并发症发生率低于对照组(P<0.05)。结论甲状腺结节患者采用甲状腺腺叶切除术治疗,可有效改善患者术后甲状腺激素水平,且术后并发症风险更小,可促进患者尽早康复,实现预后质量的提高。

Objective To analyze the changes and influencing factors of thyroid hormone level in patients with thyroid nodules after thyroidectomy.Methods In our hospital between December 2017 and June 2019 treated 84 patients with thyroid nodule as a team,according to the different surgical operation were divided into two groups,42 patients received total resection of the thyroid gland with the control group and observation group undergoing thyroid gland lobectomy,the comparison of two groups of clinical indicators,thyroid hormone levels and complications.Results The operation time,ambulation time and hospitalization time of the observation group were shorter than those of the control group,and the operation blood loss was less than that of the control group(P<0.05).There was no significant difference in thyroid hormone levels between the two groups before operation(P>0.05).Compared with the control group,the levels of FT_(4),FT_(3),TSH,T_(3) and T_(4) in the observation group were significantly improved at 15 days after operation(P<0.05).There was no significant difference in the levels of FT_(4),FT_(3),TSH,T_(3) and T_(4) between the two groups at 1 month after operation(P>0.05).The incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).Conclusion Lobectomy can effectively improve the postoperative thyroid hormone level in patients with thyroid nodules,and reduce the risk of postoperative complications.It can promote the early recovery of patients and improve the quality of prognosis.