宫腔镜下冷刀切除对子宫内膜息肉患者术后子宫内膜微环境的影响

Effect of hysteroscopic cold knife excision on the postoperative endometrial microenvironment in patients with endometrial polyps

目的分析宫腔镜下冷刀切除术治疗生育期女性子宫内膜息肉(EP)对其子宫内膜微环境的影响。方法选取2020年1月至2021年3月经本院确诊的EP患者64例,根据就诊先后顺序从1~64进行编号,1~32例纳入对照组采用钳夹术机械性清除病灶,33~64例纳入研究组予以宫腔镜下冷刀切除术。观察相关指标情况。结果研究组手术耗时、出血量少、住院时间均优于对照组,差异有统计学意义(P<0.05)。且研究组宫腔液IL-1β、IGF-1、IFN-γ水平明显低于对照组,差异有统计学意义(P<0.05)。研究组子宫内膜厚度、PBAC评分优于对照组,差异有统计学意义(P<0.05)。研究组复发率较对照组低、妊娠率高于对照组,差异有统计学意义(P<0.05)。结论宫腔镜下冷刀切除术治疗生育期女性EP效果理想,并能降低术后复发率,提高妊娠率。

Objective To analyze the effect of hysteroscopic cold knife resection on the endometrial microenvironment of endometrial polyps(EP)in reproductive women.Methods A total of 64 patients with EP who were diagnosed in our hospital from January 2020 to June 2021 were selected and numbered from 1 to 64 according to the order of visits.Nos.1 to 32 were included in the control group,and the lesions were mechanically removed by clamping.33-64 cases were included in the research group and underwent hysteroscopic cold knife resection.Observe the relevant indicators.Results The operation time,blood loss and hospital stay of the research group were better than those of the control group(P<0.05).The levels of IL-1β,IGF-1 and IFN-γin the uterine fluid of the research group were significantly lower than those of the control group(P<0.05).The endometrial thickness and PBAC score of the research group were better than those of the control group(P<0.05).The recurrence rate of the research group was lower than that of the control group,and the pregnancy rate was higher than that of the control group(P<0.05).Conclusion Hysteroscopic cold-knife resection for the treatment of EP in reproductive females has an ideal effect,and can reduce postoperative recurrence and increase the pregnancy rate.