摘要
目的分析本地区2016—2020年度孕产妇HBV感染情况及母婴阻断效果。方法选取孕产妇2563例,对其进行HBV血清学标志物检测,分析HBV感染孕妇的两对半检测结果、不同两对半检测结果组的肝功能、2016—2020年的母婴阻断效果。结果本地区HBV感染孕妇为128例(4.99%),单阳性者66例(51.56%);不同两对半检测结果组的HBV DNA载量比较,单阳性组较低(>1.0×10^(6)IU/mL);2016—2020年的孕妇HBV感染率、肝功能异常率、产科异常率和新生儿HBV感染率等指标呈逐渐下降趋势,差异具有统计学意义(P<0.05)。结论本地区HBV感染孕产妇的发病率处于较低水平,HBV DNA载量是重点观察指标,科学的综合母婴阻断措施能提升产科安全和传染病防控水平。
Objective To analyze the current status of hepatitis B virus(HBV)infection among pregnant and lying-in women in this region.Methods A total of 2563 pregnant and lying-in women registered were selected.The test results of two pairs of HBV-infected pregnant women,the liver function levels of different two-half test result groups,and the mother-to-child blocking effect from 2016 to 2020 were analyzed.Results There were 128 cases HBV-infected pregnant women(4.99%)in this area,and 66 cases(51.56%)were single-positive;the HBV DNA load of different two pairs and half test result groups was compared,and the single positive group was lower(>1.0×10^(6)IU/mL);from 2016 to 2020,the the HBV infection rate of pregnant women,abnormal liver function rate,obstetrics abnormal rate and neonatal HBV infection rate showed a decreasing trend,and the difference was statistically significant(P<0.05).Conclusion The incidence of HBV infection among pregnant and lying-in women in this region is at a low level,and HBV DNA load is a key observation indicator.Scientific comprehensive mother-to-child blocking measures can improve obstetric safety and infectious disease prevention and control.
作者
梅广军
Mei Guangjun(Preventive Health Care,Dagong Town Branch Center of Haian Center for Disease Control and Prevention,Haian,Jiangsu 226600,China)
出处
《实用妇科内分泌电子杂志》
2021年第22期58-60,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
乙型肝炎病毒感染
孕产妇
母婴阻断
Hepatitis B virus infection
Maternal
Mother-to-child interruption