腹腔镜手术联合孕三烯酮治疗子宫内膜异位症的临床研究

Clinical study of laparoscopic surgery combined with gestrinone in the treatment of endometriosis

目的 探究腹腔镜手术联合孕三烯酮治疗方法对于子宫内膜异位症(EMT)患者的临床治疗效果。方法 选取200例EMT患者,以随机数字法分为对照组(100例)和研究组(100例)。对照组患者使用腹腔镜手术方法进行治疗,研究组患者在对照组的基础上术后使用孕三烯酮进行治疗,两组均随访至术后2年。统计对比两组患者治疗效果,不良反应,妊娠情况以及病情复发情况。结果 研究组患者的总有效率为97.0%,显著高于对照组的88.0%,差异具有统计学意义(P<0.05);治疗期间,研究组患者不良反应发生率(3.0%)低于对照组患者(10.0%),差异有统计学意义(P<0.05);研究组患者妊娠率为42.0%,显著高于对照组的27.0%,差异具有统计学意义(P<0.05);研究组患者病情复发率为12.0%,显著低于对照组的31.0%,差异具有统计学意义(P<0.05)。结论 采取腹腔镜手术联合孕三烯酮治疗EMT的方式要明显优于单独手术治疗方式,能够提升治疗效果,降低患者的不良反应情况,同时提升患者的妊娠率,具有较高的临床价值。

Objective To explore the clinical effect of laparoscopic surgery combined with gestrinone therapy for patients with endometriosis(EMT).Methods A total of 200 EMT patients were selected and randomly divided into the control group(100cases) and the study group(100 cases).The patients in the control group were treated with laparoscopic surgery,and the patients in the study group were treated with gestrinone after surgery on the basis of the control group.both groups were followed up to 2 years after surgery.The treatment effect,adverse reactions,pregnancy and recurrence of the disease were statistically compared between the two groups.Results The total effective rate of patients in the study group was 97.0%,which was significantly higher than 88.0% in the control group,and the difference was statistically significant(P<0.05).During the treatment period,the incidence of adverse reactions in the study group(3.0%) was lower than that in the control group(10.0%),the difference was statistically significant(P<0.05);the pregnancy rate of the study group was 42.0%,which was significantly higher than that of the control group(27.0%),the difference was statistically significant(P<0.05);the disease recurrence rate of the study group was 12.0%,the study group was significantly lower than 31.0% of the control group,and the difference was statistically significant(P<0.05).Conclusion Laparoscopic surgery combined with gestrinone in the treatment of EMT is significantly better than surgery alone,which can significantly improve the treatment effect,reduce the adverse reactions of patients,and improve the pregnancy rate of patients,which has clinical value.