糖化血红蛋白检测在妊娠期糖尿病诊断中的作用分析

Role of glycosylated hemoglobin detection in diagnosing gestational diabetes mellitus

目的观察糖化血红蛋白检测在妊娠期糖尿病诊断中的作用。方法选择2019年10月至2020年10月接诊的妊娠期糖尿病患者30例为研究组,同期产检健康的30例孕妇为对照组。检测两组空腹血糖水平、糖化血红蛋白水平以及口服葡萄糖混合液后2 h血糖水平,观察两组的妊娠结局。结果研究组患者的糖化血红蛋白水平、空腹血糖水平以及口服葡萄糖混合液后2 h血糖水平均高于对照组,差异有统计学意义(P<0.05)。研究组不良妊娠结局发生率高于对照组,差异有统计学意义(P<0.05)。结论糖化血红蛋白检测能够对妊娠期糖尿病患者进行早期筛查和诊断,并为预后提供可靠的数据,值得大力推广与应用。

Objective To investigate role of glycosylated hemoglobin detection in diagnosing gestational diabetes mellitus.Methods A total of 30 patients with gestational diabetes admitted from October 2019 to October 2020 were selected as study group,and 30 healthy pregnant patients who underwent labor examinations at the same time were selected as control group.Fasting blood glucose level,glycosylated hemoglobin level and 2 h blood glucose level after oral administration of glucose mixture of patients in the two groups were detected,and their pregnancy outcomes were observed.Results The levels of glycosylated hemoglobin,fasting blood glucose and blood glucose 2 hours after oral administration of glucose mixture in the study group were significantly higher than those in the control group(P<0.05).The incidence of adverse pregnancy outcomes in the study group was significantly higher than that in the control group(P<0.05).Conclusion Glycosylated hemoglobin can be used for early screening and diagnosis of gestational diabetes and provide reliable data for prognosis,which is worthy of promotion and application.